Keywords

chemotherapy administration, chemotherapy safety, lean-sigma, prechemotherapy hydration, protocols, rapid hydration protocol, six-sigma

 

Authors

  1. Fratino, Lisa M. MSN, RN
  2. Daniel, Denise A. MS, RN
  3. Cohen, Kenneth J. MD, MBA
  4. Chen, Allen R. MHS, MD, PhD

Abstract

Our goal was to improve the efficiency of chemotherapy administration for pediatric oncology patients. We identified prechemotherapy hydration as the process that most often delayed chemotherapy administration. An aggressive hydration protocol, supported by fluid order sets, was developed for patients receiving planned chemotherapy. The mean interval from admission to achieving adequate hydration status was reduced significantly from 4.9 to 1.4 hours with a minor reduction in the time to initiate chemotherapy from 9.6 to 8.6 hours. Chemotherapy availability became the new rate-limiting process.