DDW: 'Alarming' Rise in Esophageal Cancer, Barrett Esophagus Seen in Middle-Age
Number of endoscopies performed not increasing, despite increased prevalence
Friday, May 13, 2022
Cardiometabolic Derangement ID'd in Overweight School Children
Higher levels of fasting glucose, insulin, HOMA-IR, triglycerides, ALT and lower levels of HDL-C seen in overweight school-aged children
Friday, May 13, 2022
DDW: Gallstone Disease May Predict Pancreatic Cancer Incidence
Gallstone presentation may be a missed opportunity for earlier diagnosis
Friday, May 13, 2022
DDW: Antibiotics Up Risk of Older-Onset Inflammatory Bowel Disease
Findings regardless of antibiotic class and with a dose-response relationship
Friday, May 13, 2022
Long-Term Mortality Rates Elevated for Adolescent, Young Adult Leukemia Survivors
Survival for adolescent and young adult leukemia survivors remained below general population at up to 30 years of follow-up
Friday, May 13, 2022
Cessation Program in Cancer Clinics May Reach More Tobacco Smokers
Low-burden, point-of-care program may increase access to and impact of treatment to assist tobacco cessation
Friday, May 13, 2022
50-µg mRNA-1273 Safe, Effective for Children Aged 6 to 11 Years
Estimated vaccine efficacy with two doses was 88.0 percent against COVID-19 at a time when delta was dominant circulating variant
Friday, May 13, 2022
Slight Increase Reported in Lung Cancer, Brain Tumors With Wildfire Exposure
Individuals exposed to wildfire within 50 km of residential locations in past 10 years had slightly higher incidence
Friday, May 13, 2022
Intervention Can Cut Risk for Mobility Disability in Seniors
Reduced incidence of mobility disability seen in older adults with physical frailty and sarcopenia receiving multicomponent intervention
Friday, May 13, 2022
Number of Mesothelioma Deaths Up Among Women From 1999 to 2020
However, age-adjusted death rate per 1 million women decreased significantly, from 4.83 to 4.15 from 1999 to 2020
Thursday, May 12, 2022
Rapid Recovery Seen With More Frequent Dialysis in SNFs
Rapid recovery associated with reduced mortality and fewer hospitalizations
Thursday, May 12, 2022
Most Patients Have Positive Views About AI in Medicine
However, concern expressed relating to unintended consequences, including misdiagnosis, privacy breaches, less time with clinicians
Thursday, May 12, 2022
'Tragic Milestone': One Million American Lives Lost to COVID-19
President Biden has ordered U.S. flags to be flown at half-staff in honor of those lost
Thursday, May 12, 2022
Lenacapavir Reduces Viral Load in Multidrug-Resistant HIV-1 Infection
Reduction in viral load from baseline greater with lenacapavir versus placebo among those with multidrug-resistant HIV-1 infection
Thursday, May 12, 2022
Digital Breas​t Tomosynthesis Tool Can Help Predict Breast Cancer
DBT-based risk model can predict cancer after a negative screening exam, with high discriminative performance for one-year risk
Thursday, May 12, 2022
TXA Seems Safe for Surgery in High-Risk Patients With IT Hip Fracture
No increased risk for mortality or thromboembolic complications seen with use of tranexamic acid among high-risk patients, entire cohort
Thursday, May 12, 2022
Previous Myocardial Injury Tied to Worse COVID-19 Outcomes
Significant but weaker associations with selected adverse outcomes seen for preexisting hypertension, diabetes, and ischemic heart disease
Thursday, May 12, 2022
FDA Moves to Ease Nationwide Shortage of Baby Formula
The agency's latest moves should help ease the dire situation many mothers face
Wednesday, May 11, 2022
Lack of Asthma Control More Likely With COVID-19-Related Anxiety
Second study shows most parents of children with food allergy report unchanged or decreased food allergy-specific anxiety during pandemic
Wednesday, May 11, 2022
Ban of Indoor Tanning Beds Would Reduce Cancers, Cut Costs
Intervention would yield net monetary benefit of £10.6 million and net health benefit of 530 QALYs
Wednesday, May 11, 2022
Subcutaneous Implantable Defibrillators Cut Lead-Related Complications
Risk for major lead-related complications much lower with subcutaneous ICD versus transvenous ICD
Wednesday, May 11, 2022
Recent Cancer Treatment Linked to Worse COVID-19 Outcomes
However, a history of cancer more than one year before COVID-19 diagnosis not tied to increased mortality or hospitalization
Wednesday, May 11, 2022
Company Hid Problems With COVID-19 Vaccines From FDA
Nearly 400 million doses of vaccine made by Emergent had to be destroyed 'due to poor quality control'
Tuesday, May 10, 2022
Mailed At-Home Disposal Kits Up Opioid Disposal Rates
Mailed kits are a potential low-cost, scalable solution, the authors say
Tuesday, May 10, 2022
Hearing, Vision Impairment Up Odds of Cognitive Decline in Seniors
Odds of cognitive impairment increased more than eightfold for seniors with dual sensory impairment
Tuesday, May 10, 2022
Gut Dysbiosis Identified in Women With Recurrent UTI
Gut microbiome of women with a history of recurrent UTI depleted in microbial richness, butyrate-producing bacteria
Tuesday, May 10, 2022
Serious Neurologic Manifestations Tied to Worse COVID-19 Outcomes
Encephalopathy was the most common serious neurologic manifestation, occurring in 10.2 percent of adults hospitalized with COVID-19
Tuesday, May 10, 2022
PFAS, Phthalate Biomarkers Linked to Bone Mineral Density in Teens
Each doubling of serum perfluorooctanoate, overall PFAS/phthalate mixture linked to lower areal BMD in male adolescents
Tuesday, May 10, 2022
Hypertensive Disorders of Pregnancy Tied to Increased CVD Risk Later in Life
Established CVD risk factors account for 57 and 84 percent of the increased rate of CVD for preeclampsia, gestational HTN
Monday, May 9, 2022
Medicare Policy Changes Tied to Drop in Hospice Use for Dementia
Immediate and lasting reductions seen in the share of patients receiving hospice care with Alzheimer disease, related dementia code
Monday, May 9, 2022
Stronger School Lunch Standards May Help Cut Child Obesity
Change in BMI trajectory observed for low-income elementary students following implementation of the Healthy, Hunger-Free Kids Act of 2010
Monday, May 9, 2022
Colonoscopy Before Age 50 May Cut Colorectal Cancer Risk in Women
Reduced risk seen with earlier initiation of endoscopy, including lower risk for colorectal cancer diagnosed in women before 55 years of age
Monday, May 9, 2022
New-Onset Depression Common During Surgical Internship Year
Among surgical interns with no depression at baseline, 32 percent had high enough scores on mood surveys to be considered depressed
Monday, May 9, 2022
CDC Investigating 109 Cases of Severe Hepatitis Among Children
Majority of patients, who were otherwise healthy, recovered fully from their illness
Friday, May 6, 2022
COVID-19 Drug Paxlovid Might Also Fight Long COVID
Series of case reports shows some success with Paxlovid in treating patients with long COVID
Friday, May 6, 2022
Virus Found in Pig Heart Transplanted Into Man Who Later Died
Patient had been recovering fairly well from the transplant but then developed symptoms similar to an infection
Friday, May 6, 2022
2010 to 2017 Saw Increase in Uterine Cancer Mortality Rates
Mortality rates increased 1.8 percent for uterine cancer overall, 2.7 percent for nonendometrioid carcinoma
Friday, May 6, 2022
Rate of Major Complications Low With Living Donor Nephrectomy
Incidence of major complications after hand-assisted laparoscopic living donor nephrectomy low at 2.5 percent
Friday, May 6, 2022
Incidence, Mortality of Subsequent Primary Cancers Up for AYA Survivors
Five-year survivors of adolescent and young adult cancers at higher risk for developing, dying from a new primary cancer
Friday, May 6, 2022
2008 to 2017 Saw Payment, Geographical Shifts in Gender-Affirming Surgery
Findings coincided with state and federal policy changes favorable to gender-affirming surgery
Friday, May 6, 2022
Alcohol Use Disorder Deaths Up During the Pandemic
Greatest increases seen among younger persons aged 25 to 44 years
Friday, May 6, 2022
Use of Proton Beam Therapy for Newly Diagnosed Cancer on the Rise
Uptake of proton beam therapy for cancer treatment varies by clinical indication
Friday, May 6, 2022
FDA Limits Use of J&J COVID-19 Vaccine Due to Blood Clot Risk
With safer two-dose vaccines such as Pfizer and Moderna widely available, the one-dose J&J shot should be limited
Friday, May 6, 2022
Rotating Night Shifts May Hamper Healthy Aging
Findings seen in large sample of U.S. female nurses followed for 24 years
Thursday, May 5, 2022
Orteronel Misses Goal in Metastatic Hormone-Sensitive Prostate Cancer
Significant improvement seen in progression-free survival, but not overall survival, with addition of orteronel to androgen deprivation therapy
Thursday, May 5, 2022
Physicians Accept Remote Auscultation Alternative for Quarantined Patients
Remote digital auscultation of heart and lungs acceptable alternative to standard physical examination for COVID-19 patients in quarantine wards
Thursday, May 5, 2022
AI Model Predicts Response to Spinal Cord Stimulation for Chronic Pain
Combined unsupervised (clustering), supervised (classification) machine learning technique used to develop predictive model
Thursday, May 5, 2022
Asthma in Adults May Raise Risk for Subsequent Obesity
Higher risk seen for those with nonatopic disease, longer disease duration, as well as those taking oral corticosteroids
Thursday, May 5, 2022
Treatment, Outcomes for AMI Patients Compared in Six Countries
Proportion of patients admitted with STEMI who received PCI in hospital in 2017 ranged from 36.9 percent in England to 78.6 percent in Canada
Thursday, May 5, 2022
30.0 Million People of All Ages Uninsured in U.S. in 2021
For adults aged 18 to 64 years, 13.5 percent were uninsured, 21.7 percent had public coverage, 66.6 percent had private coverage
Thursday, May 5, 2022
Women, People of Color Wait Longer to See ED Doctor for Chest Pain
Among young adults presenting to ED with chest pain, men were seen more quickly and were more likely to be admitted
Thursday, May 5, 2022
HTN Not Detected Earlier With Self-Monitoring of BP in Pregnancy
Second study shows no improvement in mean systolic BP with self-monitoring versus usual care for chronic or gestational HTN
Wednesday, May 4, 2022
Only One in Five Parents Plan to Get COVID-19 Vaccine for Children Under 5 When Available
27 percent said they would 'definitely not' get their child vaccinated, 11 percent said they would do so only if required
Wednesday, May 4, 2022
Children's Mental Health Impacted by Adult COVID-19 Vaccination Rates
Stress surrounding the pandemic declined in U.S. children after vaccinations were rolled out for adults
Wednesday, May 4, 2022
Hospital Costs for Firearm Injuries Vary Widely by Region
Hospital costs for firearm injuries in the United States totaled $7.8 billion over 10 years; government insurance programs covered 42 percent of the costs
Wednesday, May 4, 2022
Medication Errors Reported Frequently by Home Care Service Nurses
Increased odds of not making medication-related errors found for nurses who had attended training within last two years versus longer period
Wednesday, May 4, 2022
Polygenic Risk Score for OA Predicts Risk for Hip, Knee Replacement
Participants with high PRS had increased risk for joint replacement; stronger association seen with hip replacement for women versus men
Wednesday, May 4, 2022
Factors ID'd for Failure of Nonoperative Treatment of Pediatric Appendicitis
Higher patient-reported pain level at presentation linked to increased risk for in-hospital treatment failure
Wednesday, May 4, 2022
Hypersensitivity Reactions to Gadolinium-Based Contrast Agents Studied
History of HSR to iodinated contrast media linked to increased risk for HSR to gadolinium-based contrast agent
Wednesday, May 4, 2022
Three More Children Have Died of Mysterious Liver Disease
Nearly 170 children in 11 countries have been diagnosed with acute hepatitis in recent months
Tuesday, May 3, 2022
Sun Protection Misinformation Still Common
Yet, six in 10 U.S. adults give themselves high marks for sun protection
Tuesday, May 3, 2022
FDA Warns of Counterfeit Home COVID-19 Test Kits
Two fakes the FDA knows of are counterfeit Flowflex COVID-19 test kits and iHealth Antigen Rapid Test Kits
Tuesday, May 3, 2022
Decrease in Youth Smoking Menthol Cigarettes After Cigarette Ban
Decrease in percentage of youth smokers who reported smoking menthol cigarettes from February to August 2020 in England
Tuesday, May 3, 2022
Response to CAR-T Cell Therapy Similar for Minority Patients
Progression-free and overall survival similar for minority, nonminority patients receiving CAR-T cell therapy for non-Hodgkin lymphoma
Tuesday, May 3, 2022
Assessment Scale Scores That Identify Light Sedation Examined
Scores best linked to ability to follow at least three commands were 4 on Sedation-Agitation Scale, −1 on Richmond Agitation-Sedation Scale
Tuesday, May 3, 2022
Effect of HF-Spinal Cord Stimulation on Chronic Pain Varies by Sex
Sex-specific differences observed for efficacy of high-frequency, low-frequency spinal cord stimulation for chronic pain
Tuesday, May 3, 2022
Male Urinary Symptoms May Indicate Mortality Risk Over Time
Findings for severity of symptoms such as incontinence and frequent nighttime urination, regardless of bothersomeness
Tuesday, May 3, 2022
Fatty Tissue Transfer Benefits Arthritic Finger Joints
Minimally invasive procedure associated with significant improvements of osteoarthritis symptoms
Tuesday, May 3, 2022
Opioid Mortality Rates Up for American Indian/Alaska Natives
1999 to 2019 saw increase in mortality rates for opioid-only and opioids in combination with other substances
Tuesday, May 3, 2022
Emphysema on CT Linked to Increased Risk for Lung Cancer
Pooled odds ratios for lung cancer increased with emphysema severity, and were higher for visual versus quantitative assessments on chest CT
Tuesday, May 3, 2022
Statistical Shape Modeling of US Images Predicts Hip Dysplasia in Infants
Statistical shape modeling of ultrasound images of stable dysplastic hips in infants predicts which hips will develop to normal, remain dysplastic
Tuesday, May 3, 2022
1.3 Million Smokers May Quit if U.S. Bans Menthol Cigarettes
Findings based on the impact seen following Canada's ban
Monday, May 2, 2022
Affirmative Action Bans Cut Percent of Underrepresented Med Students
Percentage of students from underrepresented racial and ethnic groups reduced with state affirmative action bans
Monday, May 2, 2022
Almost 30 Percent of COVID-19 Patients Develop 'Long COVID'
Factors independently associated with PASC include hospitalization for COVID-19, having diabetes, and higher BMI
Monday, May 2, 2022
AYA Solid Organ Recipients Need Support After Transfer to Adult Care
Successful retention in adult health care linked to more improved clinical outcomes, but decreases in appointment attendance seen over time
Monday, May 2, 2022
AI Tool May Help Predict Risk for Pancreatic Ductal Adenocarcinoma
Model uses features in computed tomography scans of the abdomen to help identify those at high risk for developing PDAC
Monday, May 2, 2022
Black, Hispanic Race/Ethnicity Linked to Intraoperative Occult Hypoxemia
Prevalence of intraoperative occult hypoxemia in 92 to 100 percent Spo2 range higher in Black and Hispanic versus White patients
Monday, May 2, 2022
Artificial Intelligence Cuts Miss Rate for Colonoscopies
Adenoma miss rate drops by half for both proximal and distal colon lesions
Monday, May 2, 2022
Alabama Cases of Acute Hepatitis in Children Show Link to Viruses: CDC
Three of the nine patients in Alabama were so ill that they developed liver failure, and two needed liver transplants
Saturday, April 30, 2022
New Omicron Subvariant Causing COVID-19 Spike in South Africa
Number of daily cases reported by the country has shot up from just a few hundred a few weeks ago to just over 6,000
Friday, April 29, 2022
Racial Differences Seen for Use of Proton Beam Therapy
Disparities greatest most recently and for cancers for which PBT is the recommended radiation therapy modality
Friday, April 29, 2022
Hypertensive Disorders of Pregnancy Prevalence Up From 2017 to 2019
Prevalence of pregnancy-associated hypertension and chronic hypertension increased among delivery hospitalizations
Friday, April 29, 2022
Sexual Minority Students Perceive Medical School Less Favorably
Bisexual, lesbian, or gay students have less favorable perceptions of the medical school learning environment, are more likely to report burnout
Friday, April 29, 2022
Migraine May Raise Risk for Burning Mouth Syndrome
Burning mouth syndrome is characterized by an intraoral burning sensation without a known cause
Friday, April 29, 2022
Link Between GI Issues, Internalizing Symptoms Studied in Autism
Best-fitting model in path analysis suggests bidirectional relationship between GI issues, internalizing symptoms in children with ASD
Friday, April 29, 2022
Dapagliflozin Well Tolerated in COVID-19 Patients, Regardless of eGFR
Effects of dapagliflozin on primary and secondary outcomes consistent for those with eGFR <60 and ≥60 mL/min per 1.73 m2
Friday, April 29, 2022
Racial Differences Seen for Joint Replacement Care and Outcomes
Differences seen across the continuum of care for knee, hip total joint arthroplasty for osteoarthritis
Friday, April 29, 2022
FDA Proposes Ban on Menthol Cigarettes, Flavored Cigars
Research has shown that menthol cigarettes are harder to quit than traditional tobacco products
Thursday, April 28, 2022
Moderna Asks FDA to Authorize Its COVID-19 Vaccine for Children Under 6
Preliminary analysis indicates vaccine efficacy of 51 percent among children younger than 2 years and 37 percent among children 2 to 5 years
Thursday, April 28, 2022
E.U. Says Europe Out of 'Emergency' Phase of Pandemic
Announcement is not binding and national governments within the European Union will still be able to set their own public health policies
Thursday, April 28, 2022
Medicare Advantage Plans Often Deny Coverage for Eligible, Necessary Care: Report
About 28 million older Americans have Medicare Advantage plans
Thursday, April 28, 2022
Having MS May Impact Cancer Screening, Diagnosis
Patients with multiple sclerosis and breast cancer less likely to have screen-detected breast cancer
Thursday, April 28, 2022
Hospital Outcomes Worse With Suboptimal Treatment of Hypothyroidism
Patients with clinical hypothyroidism and a high prehospitalization TSH level had longer length of stay, increased risk for readmission
Thursday, April 28, 2022
Vaccination Cuts Severe COVID-19 Risk in Heart Transplant Patients
COVID-19 vaccination is not associated with heart transplant-specific adverse events
Thursday, April 28, 2022
Consider COVID Vax History When Assessing Adenopathy on Mammo
Axillary lymphadenopathy more likely within 14 days after vaccination; persistent axillary lymphadenopathy seen up to 43 weeks later
Thursday, April 28, 2022
Weight Loss and Lifestyle Program Cuts Severity of Sleep Apnea
Change in apnea-hypopnea index greater for men receiving eight-week weight loss and lifestyle intervention in addition to usual care
Thursday, April 28, 2022
Successful Intubations Up With Nasal High-Flow Therapy in Neonates
Higher rate of successful intubation on the first try, without physiological instability in the infant, seen with use of nasal high-flow therapy
Wednesday, April 27, 2022
Pfizer Seeks FDA Approval of COVID-19 Boosters for Children Ages 5 to 11
Initial two-dose series of the Pfizer vaccine was authorized for that age group in October
Wednesday, April 27, 2022
Surgery No Better for Wrist Fracture in Older Adults
Surgical treatment not superior to nonsurgical treatment for patient-rated wrist function at 24 months in adults aged 60 years and older
Wednesday, April 27, 2022
Providers, Patients Differ in Satisfaction With Anesthesia for Eye Surgery
Provider satisfaction is not a good predictor of patient satisfaction with anesthesia during ocular surgery
Wednesday, April 27, 2022
Antibiotic Use in Under 2s May Reduce Antibody Response to Vaccines
Possible negative association of history of antibiotic prescriptions with vaccine-induced immunity seen in young children
Wednesday, April 27, 2022
Racial Disparity Seen in Use of Epidural Blood Patches for Postdural Headaches
White patients more likely than Black, Hispanic, other race patients to receive patch sooner
Wednesday, April 27, 2022
Myocarditis, Pericarditis Risk Highest After Second COVID-19 Vaccine Dose
In large cohort, there were 5.55 excess events per 100,000 vaccinees after BNT162b2 and 18.39 after mRNA-1273
Wednesday, April 27, 2022
Food Insecurity Tied to Delayed, Forgone Medical Care
Food insecurity during the pandemic disproportionately affected non-White and low-income individuals
Wednesday, April 27, 2022
Risk for Guillain-Barré Syndrome Up After Ad.26.COV2.S Vaccination
Adjusted rate ratio of 20.56 found in head-to-head comparison of Ad.26.COV2.S with mRNA COVID-19 vaccines
Tuesday, April 26, 2022
Systemic Corticosteroids Tied to Vaso-Occlusive Episodes in Sickle Cell
Association seen among children and adults with sickle cell disease; association lower for those exposed to hydroxyurea
Tuesday, April 26, 2022
Continued Monitoring Needed for Anti-VEGF Therapy in Macular Edema
Substantial improvement observed through month 12, which persisted through month 60, but lessened with fewer treatments
Tuesday, April 26, 2022
Amputation Risk Up for Black, Rural Residents With Diabetic Foot Ulcers
Risk for major leg amputation or death increased compared with overall cohort of adult Medicare patients hospitalized with diabetic foot ulcers
Tuesday, April 26, 2022
Asthma, Atopy Risks Up in Offspring Born Via Infertility Treatment
Long-term follow-up of children shows increased asthma/allergy risk, independent of parental history of asthma and atopy
Tuesday, April 26, 2022
American Association for Cancer Research, April 8-13
The American Association for Cancer Research Annual Meeting
Tuesday, April 26, 2022
WHO Says Acute Hepatitis Cases in Children Now Reported in 11 Countries
Among 169 reported cases, at least one child has died; 17 children needed liver transplants
Monday, April 25, 2022
No Increased Risk for Appendicitis Reported With mRNA COVID-19 Vaccination
Findings from nationwide study in Denmark show no increased risk in association with vaccination or SARS-CoV-2 infection
Monday, April 25, 2022
Direct Provider Feedback Cuts Emergency Department Opioid Rx Rates
Intervention includes personalized feedback to clinicians and an electronic dashboard for peer comparison
Monday, April 25, 2022
Living Guideline Updated for Drug Treatment of COVID-19
Tenth version recommends nirmatrelvir/ritonavir in patients with confirmed COVID-19 who have highest risk for hospitalization
Monday, April 25, 2022
Vaccination Coverage in Kindergarteners Dropped in 2020 to 2021
3.9 percent of kindergarteners who did not have vaccine exemptions were not up to date for MMR in 2020 to 2021
Monday, April 25, 2022
Endoscopic Drainage Better for Necrotizing Pancreatitis
Rate of fistula formation and mortality lower with endoscopic drainage versus other surgical drainage methods
Monday, April 25, 2022
Vitamin D Level, Race/Ethnicity Tied to Breast Cancer Risk
Sufficient circulating vitamin D concentration linked to lower risk for breast cancer in Hispanic/Latina women
Monday, April 25, 2022
Pelvic Fixation May Not Be Needed With Cerebral Palsy Scoliosis
Indications ID'd for excluding the pelvis in children with CP scoliosis treated with growth-friendly implants
Monday, April 25, 2022
Patient-Reported Outcomes + Wearable Data Predict Postop Adverse Events
Findings seen among women with gynecologic cancers followed for four weeks
Monday, April 25, 2022
Male Teens With Sickle Cell Disease Unaware of Related Fertility Issues
Authors say educational materials and fertility testing options are needed
Friday, April 22, 2022
Drug Interaction Checkers Could Have Caught Adverse Events
More than three-quarters of COVID-19-associated drug-drug interactions could have been identified
Friday, April 22, 2022
Philadelphia Lifts Indoor Mask Mandate Enacted Four Days Ago
City's Board of Health voted during a Thursday night meeting to rescind the mandate
Friday, April 22, 2022
Adding Tislelizumab to Chemo Slows Advanced Nasopharyngeal Cancer
Progression-free survival prolonged with tislelizumab + chemotherapy versus chemotherapy alone in recurrent/metastatic NPC
Friday, April 22, 2022
Guideline Issued for Preventing SSI After Major Extremity Trauma
AAOS developed 14 strong and moderate-strength recommendations to decrease surgical site infections after major extremity trauma
Friday, April 22, 2022
Development of a Clinical Polygenic Risk Score Assay Described
Physician- and patient-oriented informational materials developed to support decision-making about polygenic risk scores
Friday, April 22, 2022
NSAIDs May Interfere With Efficacy of Bisphosphonates
No reduction in osteoporotic fracture risk seen among women receiving concomitant clodronate and NSAIDs
Friday, April 22, 2022
Guidelines Updated for Barrett Esophagus Diagnosis, Management
Guideline revised to synthesize current best practices in the management of Barrett esophagus
Friday, April 22, 2022
Inhaled Nitric Oxide Tied to Improved P/F Ratio in COVID-19 With ARDS
Improvement in mean P/F ratio with no reported toxicity observed among patients hospitalized with COVID-19 and mild-to-moderate ARDS
Friday, April 22, 2022
Mitapivat Superior to Placebo for Pyruvate Kinase Deficiency
Early, sustained, clinically significant hemoglobin response seen in 40 percent of patients receiving mitapivat versus none in the placebo group
Friday, April 22, 2022
Upper Airway Stimulation Effective in Teens With Down Syndrome, OSA
73.2 percent of patients had AHI of less than 10 events/hour at 12 months; improvement also seen in quality of life
Thursday, April 21, 2022
COVID-19-Linked Hospitalization Up for Children During Omicron
87 percent of 397 children hospitalized during omicron predominance unvaccinated; 34 percent of unvaccinated children were Black
Thursday, April 21, 2022
Medical Financial Hardship Tied to Higher Mortality in Cancer Survivors
Health insurance coverage played critical role in this association for adults aged 64 years and younger
Thursday, April 21, 2022
Sharp Spike Seen in Air Pollution Levels in Recent Years
A climate change-driven increase in wildfires may be one of the reasons for the worsening air pollution nationwide
Thursday, April 21, 2022
Opioid-Related Deaths on the Rise in Ontario, Canada
A shift in the age distribution of opioid-related mortality has occurred with the highest rates now observed in younger individuals
Thursday, April 21, 2022
AACR: Novel COVID-19 Vaccine Aimed at Immunocompromised Patients
CoVac-1, a peptide vaccine, induces T-cell immune responses in those with B-cell deficiencies, particularly leukemia and lymphoma patients
Thursday, April 21, 2022
Sex Hormone Deficiency May Up Risk for Rotator Cuff Repair
Odds of rotator cuff repair increased for women with estrogen deficiency and for men with testosterone deficiency
Thursday, April 21, 2022
Ivosidenib + Azacitidine Ups Event-Free Survival in IDH1-Mutated AML
Event-free survival significantly longer compared with placebo and azacitidine for newly diagnosed IDH1-mutated AML
Thursday, April 21, 2022
Early Effectiveness Assessed for Fourth Dose of BNT162b2 Vaccine
Difference in absolute risk for three versus four doses was 180.1 and 68.8 cases per 100,000 for COVID-19-related hospitalization, severe COVID-19
Thursday, April 21, 2022
Non-O Blood Type Time-Dependent Predictor of VTE in Cancer
In patients with intermediate or low thrombotic risk tumor types, non-O blood type linked to increased VTE risk
Thursday, April 21, 2022
Many Medicare Beneficiaries Do Not Fill High-Price Prescriptions
Among beneficiaries without low-income subsidy, noninitiation reported in 30 percent of those with new prescriptions for anticancer drugs
Wednesday, April 20, 2022
Adherence to Mediterranean-Style Diet May Cut Preeclampsia Risk
Odds of preeclampsia lower with greatest level of adherence to Mediterranean-style diet; similar benefit observed for Black women
Wednesday, April 20, 2022
Awake Prone Positioning No Benefit for COVID-19-Linked Hypoxemia
Evidence shows worse clinical outcomes on day 5 for the intervention group versus the usual-care group
Wednesday, April 20, 2022
More Than One in Seven Have a Headache on Any Given Day
New review shows headache disorders are a global burden
Wednesday, April 20, 2022
Weight Loss Surgery Effective Regardless of Age of Teens
Patient age should not be a barrier to weight loss surgery
Wednesday, April 20, 2022
Major Airlines Drop Mask Mandate After Federal Judge Rules Against It
U.S. Transportation Security Administration will stop enforcing the mandate for now
Tuesday, April 19, 2022
Transgender, Gender-Questioning Teens Have Worse Health Outcomes
On most measures in five domains of health, transgender adolescents reported differences from cisgender adolescents
Tuesday, April 19, 2022
Role of Race in Calculating UTI Risk in Children Reassessed
Race as a variable in risk prediction model can be replaced by history of UTI and duration of fever without affecting accuracy
Tuesday, April 19, 2022
Conjunctival Swab Positivity 12.7 Percent for SARS-CoV-2 Patients
Among hospitalized patients with SARS-CoV-2, eyes with CS positivity had significantly higher conjunctival redness grade
Tuesday, April 19, 2022
Role of Molecular Factors in BMI, Endometrial Cancer Link Studied
Evidence of mediating role seen for fasting insulin, bioavailable testosterone, and sex-hormone binding globulin
Tuesday, April 19, 2022
Psychological Factors Determine Poor Prognostic Outcome in IBD
Increased rates of glucocorticoid prescription or flare, escalation, death for those with clinical activity, symptoms of a common mental disorder
Tuesday, April 19, 2022
Achieving Treatment Goals in T2DM Can Up Life Expectancy
Life expectancy gains seen with reducing HbA1c, SBP, LDL-C, and BMI among individuals with type 2 diabetes
Tuesday, April 19, 2022
Use of Extrapolation Common in FDA New Drug Approvals
Extrapolation of the findings from pivotal clinical trials to the approved indication most common for disease severity
Tuesday, April 19, 2022
Cardiovascular Mortality Down Among Dialysis Patients
Greater declines seen for myocardial infarction, stroke, and pulmonary embolism among dialysis patients than general population
Tuesday, April 19, 2022
Acetaminophen Label Changes Not Linked to Accidental OD Admission
Monthly rates of hospital admission for accidental acetaminophen overdose unchanged over study period
Tuesday, April 19, 2022
PDE5 Inhibitors Prescribed for Men on Oral Nitrates for IHD
Among men with ischemic heart disease, coprescription of nitrates and PDE5 inhibitors not linked to increased risk for cardiovascular events
Monday, April 18, 2022
Parathyroidectomy No Better for Mild Primary Hyperparathyroidism
No reduction seen in mortality or key morbidities, including CV events, cerebrovascular events, cancer, peripheral fractures, kidney stones
Monday, April 18, 2022
Vijoice Granted First Approval for Treatment of PROS
Real-world data show 27 percent of patients with PIK3CA-related overgrowth spectrum treated with Vijoice had radiological response at 24 weeks
Monday, April 18, 2022
Health Officials Investigate Mysterious Hepatitis Cases Among Children in U.S., U.K.
In Alabama, the state has reported nine cases of hepatitis in children aged 1 to 6 years since October 2021
Monday, April 18, 2022
Most Cancer Centers Do Not Disclose Payer-Specific Prices
Median drug price markups across centers ranged from 120 to 630 percent
Monday, April 18, 2022
Many Doctors Unaware of Benefits of E-Cigarettes for Quitting Smoking
Survey shows many doctors less likely to recommend e-cigarettes for people seeking to quit smoking
Monday, April 18, 2022
Adverse Effects Generally Mild After BNT162b2 mRNA Booster in Over 60s
Thirty percent of those aged 60 years or older receiving booster reported at least one AE; few sought medical attention
Monday, April 18, 2022
Health Supervision Discussed for Children With Down Syndrome
Guidance provided for counseling of pregnant women with prenatal diagnosis, care of the child from infancy through adolescence
Monday, April 18, 2022
Review Shows High Prevalence of Fatigue in Adults With IBD
Prevalence of fatigue varied based on definition of fatigue and disease status
Monday, April 18, 2022
Impact of Method for Assessing Occupational Pesticide Exposure Examined
Method for assessing occupational pesticide exposure seems not to influence risk estimates for prostate cancer, NHL, Parkinson disease
Monday, April 18, 2022
Blood Biomarkers May Help ID Primary CNS Lymphoma, High-Grade Glioma
Systemic inflammatory biomarkers may be useful in the differential diagnosis of primary central nervous system lymphoma, high-grade glioma
Monday, April 18, 2022
Local Interventions Can Reduce Opioid Rx After Urologic Surgery
A systematic review and meta-analysis show direct interventions have a greater impact on opioid prescribing than indirect interventions
Monday, April 18, 2022
Marketing of Shockwave Therapy for Erectile Dysfunction Raises Concerns
Techniques, costs, and provider credentials in biggest U.S. cities vary widely
Monday, April 18, 2022