Drug Updates

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 Drug News

 Medication Errors
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Drug News

(From Facts & Comparisons)

The FDA has approved solifenacin succinate 5 and 10 mg tablets, the generic equivalent to VESIcare, indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.

The FDA has approved an expanded indication for Pradaxa (dabigatran etexilate mesylate) capsules to include the treatment of deep venous thrombosis (DVT) and pulmonary embolism (PE) in patients who have been treated with a parenteral anticoagulant for 5 to 10 days, and to reduce the risk of recurrent DVT and PE in patients who have been previously treated.

The FDA has approved an expanded indication for Kalbitor (ecallantide) to include the treatment of acute attacks of hereditary angioedema in patients 12 years of age and older.

  Medication Errors
In the January 2014 issue of Nurse Advise-ERR, the Institute for Safe Medication Practices announced the launch of the 2014-15 Targeted Medication Safety Best Practices for Hospitals. This focus of this program is to target “specific error-related issues that continue to harm patients or cause death.” The best practice recommendations include:
  • To avoid intrathecal administration, dispense vinCRIStine (and other vinca alkaloids) in a minibag of a compatible solution and not in a syringe.
  • To avoid daily administration of oral methotrexate, ensure a weekly dosage regimen default and patient education by a pharmacist for all weekly oral methotrexate discharge orders.
  • To avoid confusion between pounds and kilograms, measure and express patient weights in metric units only and ensure that scales are set and measure only in metric units.
  • To avoid the administration of oral medications by the I.V. route, ensure that oral liquids are dispensed by the pharmacy in an oral syringe and marked “Oral Use Only.”
  • To avoid confusing gradations on oral syringes, use oral liquid dosing devices that display only the metric scale.
  • To avoid harm from the use of glacial acetic acid, remove and safely discard this from all clinical areas of the hospital.

Reference

Institute for Safe Medication Practices. (2014). 2014-15 Targeted Medication Safety Best Practices for Hospitals. Retrieved from Institute for Safe Medication Practices.
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The Nursing2014 Drug Handbook -- Find complete monographs for more than 900 generic and nearly 3,000 trade drugs—including essential details on 31 NEW drugs—with important nursing considerations for each and every one in the 34th edition of the Nursing2014 Drug Handbook.