BRAF Inhibitors, (MAP) Kinase Pathway, MEK Inhibitors, Melanoma



  1. Smith, Vanessa
  2. Walton, Shernaz


ABSTRACT: We discuss the recent breakthroughs in the treatment of metastatic malignant melanoma. New therapies, which target the mitogen-activated protein kinase pathway, such as BRAF inhibitors and MEK inhibitors, may provide hope for those with metastatic disease where, historically, treatment has not been successful.