1. Olfert, Melissa D. DrPH, RDN
  2. Clark, Rashel L. MS, RDN
  3. Famodu, Oluremi A. PhD, RDN
  4. Murray, Pamela J. MD
  5. Olfert, I. Mark PhD
  6. Downes, Marianne T. PhD
  7. McFadden, Joseph W. PhD
  8. Cuff, Christopher F. PhD
  9. Colby, Sarah E. PhD, RDN
  10. Morrell, Jesse S. PhD


To develop and validate a metabolic syndrome (MetS) risk score, young adults completed an in-person assessment and online health history questionnaire. Risk scoring was based on weighted multivariate risk score functions. The area under the curve was 0.86 (95% CI, 0.32 to 0.81), indicating a significant relationship between higher scores and increased odds of MetS diagnosis (OR = 1.7; 95% CI, 1.38 to 2.25). The new score was associated with the MetS Severity Score (r [correlation coefficient] = 0.42; 95% CI, 0.31 to 0.51; P < .0001) and the American Heart Association score (r = -0.49; 95% CI, -0.57 to -0.39; P < .0001). This score can help improve primary prevention intervention strategies for young adults at risk of MetS.