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Blood coagulation disorders, Blood transfusion, Emergency medical service, Resuscitation, Wounds and injuries



  1. Estebaranz-Santamaria, Cristina PhD, BSN, MSN
  2. Palmar-Santos, Ana Maria PhD, BSN
  3. Pedraz-Marcos, Azucena PhD, BSN


Background: Massive transfusion (MT) in trauma is initiated on the basis of factors of different natures and depending on protocols and scales used both in prehospital and in-hospital care areas.


Objective: The main goal was to analyze and relate factors and predictive variables for MT requirements considering both health care areas.


Method: This was a retrospective cohort study that included patients who were treated either at the emergency department of a large hospital or through prehospital care before arrival at the hospital. The patients included were adults who received MT, defined as a blood bank request of 10 or more units of red cells in the first 24 hours or 5 or more within 4 hours of trauma, from January 1, 2009, to January 1, 2017. The variables included were individual characteristics and those associated with the trauma, clinical-analytical assessment, resuscitation, timing, and survival.


Results: A total of 52 patients who received MT were included. The average age of the patients was 41.23 +/- 16.06 years, a mean of 19.56 +/- 12.77 units was administered, and the mortality rate was 21.2%.


Discussion: Injury mechanism, clinical-analytical variables, and resuscitation strategies have a significant influence on the need for MT; therefore, early identification is fundamental for performing quality management and addressing avoidable factors during MT processes.