Abstract
Omega-3 fatty acids are known to reduce platelet aggregation and decrease risk of cardiovascular or cerebrovascular disease. Currently, there are no published systematic reviews that address the effect of omega-3 supplementation after a cerebral injury. This review addresses the benefit of omega-3 supplementation after intracranial injury, including traumatic brain injury and intracranial hemorrhage. Five studies met all of the inclusion criteria and were included in the review. Two trials reported improved clinical outcomes, measured as incidence of postoperative bleeding and symptomatic or cerebral vasospasm, while 3 saw no impact from omega-3 supplementation. In conclusion, omega-3 fatty acid supplementation may be beneficial in patients who have experienced intracranial injury.