Abstract
The practice of tight glycemic control using an intravenous insulin infusion has been adopted in many clinical settings, and although beneficial patient outcomes have been clearly documented, the therapy poses potential risks to patient safety related to hypoglycemia and increases nursing workload. This article examines these issues through a review of current research on tight glycemic protocols. Strategies for nurse leaders are provided to improve patient safety and support bedside nurses in the administration of insulin infusion protocols.