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Lippincott Nursing Pocket Card - January 2021
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Septic shock is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of mortality (Singer et al., 2016). Early diagnosis and treatment has been shown to improve patient outcomes and decrease overall mortality from sepsis.
Sequential (Sepsis-Related) Organ Failure Assessment (SOFA) Score (Vincent et al., 1996)
Score
0
1
2
3
4
Respiration
PaO2/FiO2 mm HG (kPa)
≥ 400 (53.3)
< 400 (53.3)
< 300 (40)
< 200 (26.7) with respiratory support
< 100 (13.3) with respiratory support
Coagulation
Platelets, x 103/uL
≥ 150
< 150
< 100
< 50
< 20
Liver
Bilirubin, mg/dL (umol/L)
< 1.2 (20)
1.2- 1.9 (20- 32)
2.0-5.9 (33- 101)
6.0-11.9 (102 -204)
> 12.0 (204)
Cardiovascular
Mean arterial pressure (MAP) and vasopressor therapy (ug/kg/min for at least 1 hour)
MAP ≥ 70 mmHg
MAP < 70 mmHg
Dopamine < 5 or dobutamine (any dose)
Dopamine 5.1-15 or epinephrine ≤ 0.1 or norepinephrine ≤ 0.1
Dopamine > 15 or epinephrine > 0.1 or norepinephrine > 0.1
Central Nervous System
Glasgow Coma Scale score
15
13-14
10-12
6-9
< 6
Renal
Creatinine, mg/dL (umol/L)
< 1.2 (110)
1.2-1.9 (110-170)
2.0-3.4 (171-299)
3.5-4.9 (300-440)
> 5.0 (440)
Urine output, mL/day
< 500
< 200
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