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epidermolysis bullosa (EB), skin diseases, EB simplex, junctional EB, dystrophic EB, Kindler syndrome



  1. Pope, Elena MD, MSc, FRCPC
  2. Lara-Corrales, Irene MD, FRCPC (Derm)
  3. Mellerio, Jemima E. BSc, MD, FRCP
  4. Martinez, Anna E. MBBS,MRCP,MRCPCH
  5. Sibbald, Cathryn RPh, BScPhm, ACPR
  6. Sibbald, R. Gary BSc, MD, MEd, FRCPC (Med) (Derm), FACP, FAAD, MAPWCA, for the EB International Consensus Panel


PURPOSE: To enhance the learner's competence with information about a wound bed preparation model of fragile skin for patients with epidermolysis bullosa (EB).


TARGET AUDIENCE: This continuing education activity is intended for physicians and nurses with an interest in skin and wound care.


OBJECTIVES: After participating in this educational activity, the participant should be better able to:


1. Differentiate between the types and subtypes of EB. 2. Apply EB assessment and treatment strategies to patient care scenarios.


ABSTRACT: Epidermolysis bullosa (EB) is a group of inherited diseases with 4 subtypes. This disorder is a model for fragile skin, with some affected individuals having chronic, difficult-to-heal wounds. The care of wounds in people with EB can be guided by the Wound Bed Preparation paradigm. The treatment of chronic EB wounds is outlined with a quick reference guide of 12 consensus recommendations created by a panel of 11 experts. These recommendations were reviewed by a computer-facilitated modified Delphi process where 15 external reviewers (68.8% of whom reported having 11 or more years' experience with EB care). Inclusion of recommendations was contingent on 80% agreement from reviewers.