Authors

  1. Kilincalp, Serta MD
  2. Coban, Sahin MD[spacing cedilla]
  3. Yuksel, Ilhami MD

Article Content

To the Editor,

 

A 33-year-old-man was admitted to our outpatient clinic for dyspeptic complaints. A routine upper gastrointestinal endoscopy was performed by an experienced endoscopist without sedation. The patient suffered from multiple sustained Valsalva maneuvers during the procedure. Shortly after the procedure, he reported painless blurred vision and frightening red appearance in his eyes (Figure 1).

  
Figure 1 - Click to enlarge in new windowFIGURE 1. Valsalva retinopathy following endoscopic procedure.

His medical history was unremarkable, and he did not receive any medication. Blood pressure, full blood count, coagulation profile, and sickle cell tests were all within normal limits. Additional tests for a hypercoaguable state and autoimmune diseases were negative. Retinal examination showed subhyaloid hemorrhage overlying the macula. On the basis of the history and retinal examination, the patient was diagnosed with Valsalva retinopathy. The hemorrhage resolved spontaneously and the patient's vision returned to normal within a month without any consequences.

 

Valsalva's hemorrhagic retinopathy was first described in 1972 for the retinal hemorrhages that occurred immediately after heavy lifting, coughing, vomiting, or straining. Valsalva maneuvers cause a sudden increase in intrathoracic, intra-abdominal, and intraocular venous pressure. Valsalva retinopathy occurs when this increased retinal venous pressure may cause local rupture of superficial retinal capillaries and leads to retinal hemorrhage (Albert & Jakobiec, 2000) (see Figure 1).

 

Both vomiting and labor cause increased intrathoracic pressure against a closed glottis (Wickremasinghe, Tranos, & Davey, 2003). Valsalva retinopathy usually occurs in healthy individuals when this increased intrathoracic pressure transmitted to the eye causes a sudden rise in the intraocular venous pressure leading to spontaneous rupture of superficial retinal capillaries. Valsalva maneuvers typically result in superficial retinal hemorrhages with a predilection for the macula. Patients usually give a history of sudden visual loss following an event that diminishes the intrathoracic pressure like heavy lifting, blowing balloons, straining, coughing, or vomiting (e.g., in pregnancy) (Hassan & Tajunisah, 2011).

 

Although it can alarm the patient and possibly the physician, the prognosis of Valsalva hemorrhagic retinopathy is generally good. It is a self-limited event and in most cases, the hemorrhage resolves within a month without any sequelae. These patients, however, should be referred for ophthalmologic evaluation and follow-up because the hemorrhage may cause a visual loss of up to 6 months if left untreated (Rennie, Newman, Snead, & Flanagan, 2001). To avoid complications, hemorrhage may be managed with laser therapy (Kwok, Lai, & Chan, 2003).

 

Adequate explanation of the procedure and sufficient sedation may prevent this potential ocular complication, especially in vulnerable patients with diabetes mellitus and bleeding tendency (Chan, Liu, Tham, Wu, & Lam, 2003; O'Hanley & Canny, 1985). To our knowledge, this is the second report of the occurrence of Valsalva retinopathy following a routine upper gastrointestinal endoscopy.

 

Serta Kilincalp, MD

 

Gastroenterology Fellow

 

Department of Gastroenterology

 

Ankara D[latin dotless i]s[spacing cedilla]kap[latin dotless i] Y[latin dotless i]ld[latin dotless i]r[latin dotless i]m Beyaz[latin dotless i]t Education and Research Hospital

 

Ankara, Turkey

 

D[latin dotless i]s[spacing cedilla]kap[latin dotless i] Education and Research Hospital Gastroenterology Clinic

 

Alt[latin dotless i]ndag[spacing breve], Ankara, Turkey

 

S[spacing cedilla]ahin Coban, MD

 

Associate Professor

 

Department of Gastroenterology

 

Ankara D[latin dotless i]s[spacing cedilla]kap[latin dotless i] Y[latin dotless i]ld[latin dotless i]r[latin dotless i]m Beyaz[latin dotless i]t Education and Research Hospital

 

Ankara, Turkey

 

Ilhami Yuksel, MD

 

Department of Gastroenterology

 

Ankara D[latin dotless i]s[spacing cedilla]kap[latin dotless i] Y[latin dotless i]ld[latin dotless i]r[latin dotless i]m Beyaz[latin dotless i]t Education and Research Hospital

 

Ankara, Turkey

 

Department of Gastroenterology

 

Ankara Y[latin dotless i]ld[latin dotless i]r[latin dotless i]m Beyaz[latin dotless i]t University Hospital

 

Ankara, Turkey

 

REFERENCES

 

Albert D. M., Jakobiec F. A. (2000). Principles and Practice of Ophthalmology (2nd ed., Vol. 2). Philadelphia, PA: Saunders. [Context Link]

 

Chan W. M., Liu D. T., Tham C. C., Wu R. M., Lam D. S. (2003). Bilateral subhyaloid haemorrhage in aplastic anaemia. British Journal of Haematology, 123, 757. [Context Link]

 

Hassan M., Tajunisah I. (2011). Valsalva haemorrhagic retinopathy after push-ups. Lancet, 377(9764), 504. [Context Link]

 

Kwok A. K., Lai T. Y., Chan N. R. (2003). Epiretinalmembrane formation with internal limiting membrane wrinkling after Nd:YAG laser membranotomy in Valsalva retinopathy. American Journal of Ophthalmology, 136, 763-766. [Context Link]

 

O'Hanley G. P., Canny C. L. B. (1985). Diabetic dense premacular hemorrhage. Ophthalmology, 4, 507-511. [Context Link]

 

Rennie C. A., Newman D. K., Snead M. P., Flanagan D. W. (2001). Nd:YAG laser treatment for premacular subhyaloid haemorrhage. Eye, 15, 519-524. [Context Link]

 

Wickremasinghe S., Tranos P., Davey C. (2003). Valsalva retinopathy in a pregnant woman: Implications for delivery. Acta Ophthalmologica, 81, 420. [Context Link]