Biologics, Biomarkers, Cardiovascular Risk, Psoriasis



  1. Gillespie, Tara


ABSTRACT: Psoriasis is a skin disease associated with systemic inflammation affecting many people in today's society. Prevalent studies support a relationship between systemic inflammation and increased cardiovascular disease in these patients. The purpose of this article is to provide the research evidence that assessed the relationship between systemic treatments such as biologic agents for psoriasis and their effects on cardiovascular risk factors. The review of literature illustrates that patients treated with biologic agents have significantly lower cardiovascular disease as evidenced by biomarkers. Levels of evidence for each research study were assigned using a rating system. Findings, implications, and the need for further research on this topic are discussed.