1. Wood, Kevin MD
  2. Vokes, Everett MD


Options for patients with locoregional recurrence include surgical resection if a small, isolated mass is staged. The extent of recurrent disease is significant in dictating likelihood of cure and length of overall survival after surgical resection. In a large meta-analysis, median survival was in excess of 24.3 months for limited, isolated disease but decreased to 9.3 months for more extensive disease (P = 0.0006). Reported 5-year overall survival rates after salvage surgery range from 11 to 39 percent