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  1. Henke, Kim RN, MPA, MSN
  2. Eigsti, Janice RN, BSN, CCRN


Despite significant advances made in cardiac surgery over the last 2 decades, the process of bypassing the heart and lungs or cardiopulmonary bypass (CPB) continues to precipitate physiologic insults that have an impact on a patient's ability to recover from open-heart surgery. This article explores some of these potential insults and reviews some of the interventions used to neutralize the impact of CPB.