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  1. Helm, Robert E. MD
  2. Klausner, Jeffrey D. MD, MPH
  3. Klemperer, John D. MD
  4. Flint, Lori M. BSN, RN, CCRN
  5. Huang, Emily BA


Peripheral intravenous (IV) catheter insertion, the most common invasive hospital procedure performed worldwide, is associated with a variety of complications and an unacceptably high overall failure rate of 35% to 50% in even the best of hands. Catheter failure is costly to patients, caregivers, and the health care system. Although advances have been made, analysis of the mechanisms underlying the persistent high rate of peripheral IV failure reveals opportunities for improvement.