fatigue, mobile phone-based application, multiple sclerosis, quality of life



  1. Newland, Pamela
  2. Oliver, Brant
  3. Newland, John M.
  4. Thomas, Florian P.


BACKGROUND: Fatigue is a significant and burdensome symptom for patients with multiple sclerosis and is associated with other symptoms, signs, and decreased quality of life.


METHODS: A prospective pilot study was conducted with a convenience sample (n = 34) of patients with relapsing-remitting multiple sclerosis using a phone application,, to collect data on patient-reported outcome measures (Patient-Reported Outcomes Measurement Information System [PROMIS]).


RESULTS: FatigueApp feasibility was good, with the ability to collect data on self-reported fatigue and other symptoms using PROMIS measures.


CONCLUSIONS: This study showed that using a phone application with PROMIS may be useful in the future to provide estimates of fatigue and other variables to facilitate clinical monitoring of fatigue for neurology clinic settings.