1. Owusu, Kent A. PharmD, BCCCP, BCPS
  2. Saliba, Lina PharmD, BCCCP, BCPS
  3. Ammar, Abdalla A. PharmD, BCCCP, BCPS
  4. Ammar, Mahmoud A. PharmD, BCCCP, BCPS
  5. Mucksavage, Jeffrey PharmD, BCPS


Medicinal cannabinoid use continues to evolve across the United States, although legitimate federal recognition for medicinal purpose is lacking. Variability exists across states within the United States with respect to legislation, and health care institutions encounter challenges when patients present with a history of medicinal cannabinoid use. Emerging evidence in the field of neurosciences suggests a role of cannabinoids for neurologic medical conditions such as Parkinson disease, multiple sclerosis, and epilepsy. We aim to provide an overview of cannabinoids including a historical perspective, pharmacology, applications in neurosciences, and challenges in health care and academia. Knowledge of the appropriate role of cannabinoids in the clinical setting is essential for all health care practitioners including nursing.