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corticosteroids, infection, immunosuppressants, pyoderma gangrenosum, superimposed infection



  1. Gavioli, Elizabeth M. PharmD
  2. Casias, Michael PharmD
  3. Ngo, Linda PharmD


ABSTRACT: Pyoderma gangrenosum (PG) is a rare, ulcerating, inflammatory disease that is often misdiagnosed as a skin and soft tissue infection. If PG is identified, it is treated with topical or systemic immunosuppressants to reduce inflammation and induce remission. However, the use of immunosuppressants has been linked to a higher risk of superimposed infections. The authors report the case of a 24-year-old female patient with bilateral lower extremity PG with a superimposed infection of Pseudomonas aeruginosa and Bacteroides fragilis after intralesional corticosteroid therapy.