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New U.S. cancer diagnoses plummeted with the onset of COVID-19. In a research letter published August 3 in JAMA Network Open, researchers report a 46% decline from March 1 to April 18 in new diagnoses of six types of cancer combined, ranging from 25% for pancreatic cancer to 52% for breast cancer. This drop is being seen in other countries as well, such as the United Kingdom, where referrals for cancer decreased by 75% during the same period. COVID-19 restrictions and fear of exposure to the virus has led to a steep decline in cancer screening; for some tests, such as mammograms and colonoscopies, as much as a 90% decrease. In a June editorial in Science, Dr. Norman Sharpless, director of the National Cancer Institute, warns that the delays in diagnoses and treatment could result in thousands of excess deaths in the next 10 years.