1. Navarro Correal, Ester MSN, RN
  2. Casellas Jorda, Francesc MD, PhD
  3. Borruel Sainz, Natalia MD, PhD
  4. Robles Alonso, Virginia MD, PhD
  5. Herrera de Guise, Claudia MD, PhD
  6. Ibarz Casas, Arantxa MSN, RN
  7. Sanchez Garcia, Josep Maria MD
  8. Vila Morte, Genoveva RN
  9. Fuentelsaz Gallego, Carmen RN, PhD


A randomized, open-label, controlled clinical trial was designed to assess the effectiveness of a motivational intervention based on the 5 R's model (relevance, risks, rewards, roadblocks, and repetition) delivered by specialized inflammatory bowel disease nurses every 3 months over a 1-year period as compared with patients who were followed regularly. Patients diagnosed with Crohn disease, aged 18 years or older, who reported being active smokers with Internet access at home and an e-mail address were eligible. A total of 144 patients (72 per group) were included (50% women, median age 40 years). They smoked a median of 10 cigarettes per day (range = 1-40) and had been smoking for a median of 22 years (range = 1-51). Motivation to quit (Richmond test) was low in 73 patients, moderate in 39 patients, and high in 32 patients. Statistically significant differences between the study groups in the predisposition to change, motivation to quit, and tobacco withdrawal were not found. However, 14 patients (20.9%) in the intervention group and 9 patients (13.2%) among controls stopped smoking at the end of the study. These findings support a higher trend toward smoking cessation associated with the motivational intervention 5 R's. This behavioral strategy can aid patients with Crohn disease to quit smoking.