1. Briete, Lauren D. PharmD
  2. Towers, William F. PharmD, BCPS
  3. Bone, Rachel PharmD, BCPS
  4. Nair, Ranjit AGACNP-BC
  5. Steck, Mackenzie PharmD, BCPS
  6. Cutshall, B. Tate PharmD, BCPS
  7. Shah, Samarth P. PharmD, BCPS


Management of anticoagulation in individuals undergoing operative procedures is a complex situation. Each case should be assessed individually with proper risk assessment, monitoring, and plan for perioperative and postoperative anticoagulation. Clinical evidence for the management of these patients is relatively scarce, and clinicians are often assessing each individual case with minimal guidance. This review provides nurses with a summary of available literature on the assessment, laboratory monitoring, timing of adjusting anticoagulation, and bridging prior to procedures. In addition to general perioperative anticoagulation management, this review discusses perioperative management in special populations and provides a summary on principles when anticoagulation should be resumed following a procedure.