1. Culbertson, Amy DNP, APRN, FNP-BC
  2. Huey, Sally DNP, APRN, FNP-BC


Malignant melanoma incidence is rising faster than any other malignancy. Recurrent disease can occur in as many as 10% of patients diagnosed with primary malignant melanoma. In-transit melanoma is a type of locoregional disease that materializes when the cancer recurs as dermal and subdermal nodules found between the primary site and the lymph node drainage basin. Patients may not recognize the lesions as in-transit melanoma, and they may present to the emergency department for another matter completely. Ultimately, once recurrence is suspected, there must be a swift referral to oncology. Lack of recognition of this unique skin lesion could prove to be fatal. As frontline providers of care, emergency nurse practitioners should be alert to the characteristics of these lesions and the history that supports this dermatological condition.