Abstract
The abrupt dissolution of United States Agency for International Development and the cessation of U.S. President's Emergency Plan for AIDS Relief funding have triggered a global health crisis, disproportionately affecting HIV services and frontline health systems across the Global South. This article explores how nurses are responding—not only by sustaining clinical care but by stepping into roles as policy advocates, organizers, and system innovators. Drawing from lived experiences in Kenya, Malawi, the Philippines, and beyond, we highlight the resilience, leadership, and moral clarity of nurses working through institutional collapse. We argue that nursing is not only a caregiving profession but also a political force essential to rebuilding global health equity. In the face of policy-driven disruption, nurses are advancing solutions grounded in community, advocacy, and cross-border solidarity.