Sepsis Guidelines and Protocols: Providing Care to Patients

The diagnosis of sepsis is one of the most challenging. Sepsis affects millions of people worldwide and one in four of the people affected will die. The way we recognize and treat sepsis has changed over the years, and in January 2017, the International Guidelines for Management of Sepsis and Septic Shock: 2016 was published. (Here's the 2018 update.) The guidelines emphasizes that patients with sepsis should be viewed as having a medical emergency, necessitating urgent assessment and treatment. The resources in this collection focus on sepsis identification and goal-directed treatment according to current guidelines and definitions. Use these resources to improve the way you provide care to patients with sepsis.

NEW! Surviving Sepsis 2021: How does it differ from 2016?
Lippincott® NursingCenter®, October 2021

Specially-Priced NCPD Collection

NCPD Sepsis
4.5 contact hours, $21.95
Review the assessment and manifestations of sepsis and septic shock; new treatment guidelines and changes in the sepsis bundle interventions; and the use of sepsis assessment and screening tools for patients in various acute care settings.

Guideline Summaries


Nursing Pocket Card

Free Recognizing and Managing Sepsis
Lippincott® NursingCenter®, February 2022

Videos, Podcasts, & Infographics

Free Physiology Fundamentals: Sepsis [PODCAST]
Lippincott® NursingCenter®, September 2019

Free Preventing Sepsis [VIDEO]
From the Desk of the Chief Nurse, September 2017

Free Recognize Early, Act Fast! [VIDEO]
Lippincott® NursingCenter®, September 2017

Free Laboratory signs of sepsis [Infographic]
Lippincott® NursingCenter®, March 2017

Journal Articles & NCPD

Buy Improving Antibiotic Administration Rate for Patients With Sepsis in the Emergency Department
Journal of Nursing Care Quality, October/December 2021

Free Nurses' Knowledge on Sepsis Related to Mechanical Ventilation: An Intervention Study
The Journal of Nursing Research, August 2021

NCPD Maternal Sepsis: Presentation, Course, Treatment, and Outcomes
MCN, The American Journal of Maternal/Child Nursing, May/June 2021

Buy Post–Sepsis Syndrome
Critical Care Nursing Quarterly, April/June 2021

Buy Early Recognition and Management of Sepsis in the Elderly: A Case Study
Critical Care Nursing Quarterly, April/June 2021

Buy Implementation of an Automated Sepsis Screening Tool in a Community Hospital Setting
Journal of Nursing Care Quality, April/June 2021

Free Can You Escape Sepsis? Using a Healthcare Escape Room as an Innovative Approach to Nursing Education
Clinical Nurse Specialist: The Journal for Advanced Nursing Practice, March/April 2021

NCPD Neonatal Sepsis: A Review of Pathophysiology and Current Management Strategies
Advances in Neonatal Care, February 2021

Buy Long-term Renal Outcomes in Adults with Sepsis-Induced Acute Kidney Injury: A Systematic Review
Dimensions of Critical Care Nursing, September/October 2020

NCPD Sepsis: A Review for Homehealth Clinicians
Home Healthcare Now, July/August 2020

Buy A Cross-sectional Study of Group B Streptococcus-Associated Sepsis, Coinfections, and Antibiotic Susceptibility Profile in Neonates in Pakistan
Advances in Neonatal Care, August 2020

Buy Mitochondrial Dysregulation in Sepsis: A Literature Review
Clinical Nurse Specialist: The Journal for Advanced Nursing Practice, July/August, 2020

Buy Nifty Nursing Mnemonic for Early Sepsis Recognition
Nurse Educator, May/June 2020

NCPD Accelerated Biologic Aging, Chronic Stress, and Risk for Sepsis and Organ Failure Following Trauma
Journal of Trauma Nursing, May/June 2020

Buy Utilization of a Visit-Based Sepsis Assessment to Prevent Hospital Readmissions
Home Healthcare Now, May/June 2020

Buy Implementation of the Neonatal Sepsis Calculator in Early-Onset Sepsis and Maternal Chorioamnionitis
Advances in Neonatal Care, February 2020

Buy Sepsis Education Initiative Targeting qSOFA Screening for Non-ICU Patients to Improve Sepsis Recognition and Time to Treatment
Journal of Nursing Care Quality, October/December 2019

Free Sepsis in Pregnancy and Postpartum
MCN, The American Journal of Maternal/Child Nursing, September/October 2019

Buy Multidisciplinary Approach to Improve Sepsis Outcomes
Journal For Healthcare Quality, July/August 2019

Buy Decreasing the Time to Administration of First Dose of Antibiotics in Children With Severe Sepsis
Journal For Healthcare Quality, January/February 2019

Buy Early, Nurse-Directed Sepsis Care
AJN, American Journal of Nursing, January 2019

NCPD A Review of the Revised Sepsis Care Bundles
American Journal of Nursing, August 2018

Blog Posts

Free NEW! The 4 Components of Source Control in Sepsis
Lippincott® NursingCenter®, February 2022

Free Surviving Sepsis 2021: How does it differ from 2016?
Lippincott® NursingCenter®, October 2021

Free Managing Sepsis in COVID-19 Patients: What’s Different? 
Lippincott® NursingCenter®, September 2020

Free Surviving Sepsis Campaign Releases COVID-19 Guidelines
Lippincott® NursingCenter®, March 2020

Free The New “Hour-One” Sepsis Bundle: Key Takeaways and Controversies
Lippincott® NursingCenter®, June 2018

Free What is sepsis? What the public needs to know
Lippincott® NursingCenter®, September 2017

Free Sepsis: What nurses need to know
Lippincott® NursingCenter®,September 2017

Free Top 10 Things Advanced Practice Nurses Need to Know about the Updated Guidelines for Management of Sepsis and Septic Shock
Lippincott® NursingCenter®, September 2017