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Release Date : February 28 2019

Management of Primary Cutaneous Melanoma

This update to the 2011 clinical practice guideline provides recommendations for diagnosis and management of patients with primary cutaneous melanoma (CM), American Joint Committee on Cancer stages 0-IIC and pathologic stage III based on positive sentinel lymph node biopsy (SLNB). Biopsy techniques; histopathologic reporting; use of laboratory, molecular, and imaging tests for initial work-up; surgery and staged excision; staging of regional lymph nodes (LNs) with SLNB; nonsurgical treatments including imiquimod and radiation therapy (RT) for CM; pregnancy and melanoma; genetic testing for familial melanoma; and management of dermatologic toxicities related to targeted therapies and immunotherapies are included.

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