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Blood test based on four-marker protein panel combined with risk prediction model may improve assessment of risk for lung cancer

Managing Pulmonary Embolism in Primary Care Feasible for Some Patients

About 21 percent of adults diagnosed with acute PE in primary care sent home; few experienced adverse events within 30 days

Prognostic Index May ID CLL Patients Who Will Not Need Treatment

Novel prognostic index CLL-WONT identifies patients with chronic lymphocytic leukemia who are at low risk for ever requiring treatment

Overall, Night Shift Work Not Tied to Higher Lymphoma Risk

However, nonlinear association seen between night shifts and chronic lymphocytic leukemia

Black Patients More Likely to Have Negative Descriptors in Notes

Compared with White patients, Black patients have 2.54 times the odds of having at least one negative descriptor in EHR

Frailty Mars Outcomes After aHSCT in Lymphoid Malignancies

Links found for frailty with in-hospital mortality, prolonged length of stay for patients with NHL, HL, MM undergoing aHSCT

Risk for Cancer Increased After VTE for Patients With Psoriasis

Standardized incidence ratio was 3.0 during first year of follow-up after VTE and decreased to 1.5 during subsequent years

Pandemic Having Major Impact on Pediatric Oncology Providers

51 percent of institutions cite decreased clinical staff availability; HCPs experiencing psychological distress, financial concerns

Combo Immunotherapy Ups Survival in Advanced Liver Cancer

Overall survival, but not progression-free survival, improved with tremelimumab plus durvalumab versus sorafenib for unresectable HCC

Adding Immunotherapy to Chemo Ups Survival in Advanced Biliary Tract Cancer

Overall survival, progression-free survival prolonged in those receiving durvalumab versus placebo in addition to gemcitabine and cisplatin

Prolonged TV Watching Ups Blood Clot Risk

35 percent higher risk for venous thromboembolism seen with watching more than four hours of TV daily

Biosimilars Could Cut Spending for Biologic Therapy in the U.S.

Increased market growth of biosimilars that are similar to brand-name biologic agents has the potential to reduce spending on prescription drugs

Significant Health Benefits Seen With Meeting ATS Air Quality Standard

Compared with meeting EPA standards alone, this would prevent 11,850 more deaths, 25,400 more morbidities

Breast Cancer Survivors Face Higher Risk for Hypertension, Diabetes

Risk for hypertension even higher for those receiving left-sided radiation therapy, endocrine therapy

Long-Term Outcomes Described for Survivors of Childhood ALL

Life challenges more negatively impacted in younger, female, relapsed patients; socializing more positively impacted in older patients

Nomogram May Help Predict Survival in Primary Intestinal NHL

Prediction accuracy of the nomogram higher than that of Ann Arbor Stage for primary intestinal non-Hodgkin lymphoma patients

2021 USPSTF Lung Cancer Screening Criteria Expand Eligibility

Compared with 2013 USPSTF criteria, more patients eligible for lung cancer screening with less racial disparity in access

Survival Increase Seen for Adults With Relapsed Ph+ ALL

From 2000 to 2019, overall survival progressively improved for patients with Philadelphia-positive ALL who had posttransplant relapse

Guideline Issued for External Beam RT in Primary Liver Cancers

EBRT strongly recommended as potential first-line therapy for patients with HCC confined to liver who are not candidates for curative therapy

Unnecessary RT Given Near End of Life in Metastatic Cancer

Guideline-nonconcordant radiotherapy given to substantial proportion of Medicare beneficiaries with metastatic cancer near the end of life

Global Burden of Chronic Lymphocytic Leukemia Up From 1990 to 2019

Incidence higher for men versus women, adults older than 70 years, and individuals living in high social-demographic index regions

Amid U.S. Blood Shortage, New Pressure to Ease Donor Rules for Gay Men

Easing the rules would result in a 2 to 4 percent increase -- 345,400 to 615,300 more pints of blood -- in the nation's annual blood supply

Senate Committee Backs Califf Nomination to Head FDA

Among those who voted against Califf's nomination were Democrats who expressed concerns about his links to pharmaceutical companies

Supreme Court Blocks Biden's Vaccine Mandate for Large Employers

Mandate was a crucial component of the White House plan to tackle the COVID-19 pandemic

NCCN Endorses Full COVID-19 Vaccination for Cancer Patients

The NCCN Advisory Committee supports the strong preference for mRNA vaccines and offers guidance on the timing of vaccination

Data Support Lowering Age for CRC Screening to 45 Years

For those aged 45 to 49 years, 32 percent had any neoplasia, 7.5 percent had advanced premalignant lesions, 0.58 percent had CRC

Overall Breast Cancer Incidence Decreased From 1999 to 2018

Incidence increased from 2004 to 2018, and among non-Hispanic Asian or Pacific Islander women and those aged 20 to 39 years

Incidence of Advanced Lung Cancer Continues to Decline in the U.S.

During 2014 to 2018, incidence continued to increase slowly for female breast cancer, remained stable for prostate cancer

Sitting, Inactivity Increase Death Risk Among Cancer Survivors

Risk for both all-cause and cancer-specific death increased for cancer survivors with combination of prolonged sitting and inactivity

Red Cross Says U.S. Blood Supply at Dangerously Low Level

People who have received COVID-19 vaccines can donate blood and platelets as long as they are symptom-free

Young Adults With Cancer Facing Psychological Distress During Pandemic

High psychological distress tied to lower quality of life, social isolation, impaired cancer care

Factors at Midlife May Predict Health Trajectory in Women

Factors linked to health declines include higher BMI, lower level of education, current smoking, osteoarthritis, depression, CVD

Severe COVID-19 Outcomes Rare After Primary Vaccination

Risk higher for people who were aged 65 years or older, immunosuppressed, or had at least one of six underlying conditions

Psychological Distress More Likely in Young Adult Cancer Survivors

AYA cancer survivors with versus without psychological distress have additional medical expenses, office visits, use of meds

Supreme Court Hears Arguments on Biden's Vaccine Mandate for Big Business

Court also hearing arguments on separate vaccine mandate for most heath care workers

Incarceration Tied to Lower Life Expectancy in Blacks

Disparities in incarceration may partially explain the lower life expectancy of Blacks, authors say

Most of World's Urban Population Live in Areas With High PMâ‚‚.â‚…

About 86 percent of urban dwellers live in areas that exceed WHO guidelines for annual PM_2.5, contributing to >1.8 million deaths

Relatlimab-Nivolumab Ups PFS in Untreated Advanced Melanoma

Combination provides greater benefit than nivolumab alone for progression-free survival in untreated metastatic or unresectable melanoma

Eltrombopag Augments Immunosuppression in Severe Aplastic Anemia

Improvement seen in the rate, rapidity, strength of hematologic response in previously untreated patients with severe aplastic anemia

Stage Shift Tied to Decreased Population Mortality in NSCLC

Diagnostic shift from later-stage to earlier-stage disease may have implications for evaluation of treatments and mortality outcomes

Physicians Lack Knowledge About Responsibilities Under ADA

71.2 percent of the physicians answered incorrectly about who determined reasonable accommodations for patients with disability

Tailored Strategies Can Up Depression Referrals in Breast Cancer

Tailored strategies for implementation of routine depression screening result in greater proportion of referrals to behavioral care

E-Cigarettes Tied to Quitting Among Smokers Not Trying to Quit

Findings seen for both discontinuation overall and discontinuing daily smoking

Major Financial Hardship Prevalent in Metastatic Colorectal Cancer

At 12 months, cumulative incidence of major financial hardship was 71.3 percent, despite insurance cover

Maternal Hormonal Contraception, CNS Tumors Not Linked in Children

No significant association seen for recent or previous maternal hormonal contraception use with CNS tumors in children younger than 20 years

Israel Will Give Fourth COVID-19 Shot to People Older Than 60, Health Workers

About 60 percent of Israel's 9.4 million people are fully vaccinated with either a recent second dose or booster dose

Global Burden of Cancer Increasing

From 2010 to 2019, largest percentage increase in numbers of cases and deaths occurred in low and middle-low SDI quintiles

Rivaroxaban Improves Clinical Outcomes After COVID-19 Hospitalization

Risk for thrombotic events reduced after 35 days of rivaroxaban compared with no extended thromboprophylaxis

Breast Cancer Survival Up With Access to Integrative Therapies

Survival up at institutions in low-mid, mid-high cohorts based on efforts to educate, support, and fund complementary and lifestyle approaches

Primary Care Clinicians Tailor Colorectal Cancer Screening to Patients

One in four primary care clinicians select a stool-based test as their preferred screening option

Guidance Offered for Managing Pain in Patients With Cancer and OUD

For patients with opioid use disorder taking buprenorphine-naloxone, it is deemed appropriate to continue three times-daily dosing

U.S. Adults Support Net-Risk Pediatric Research

Most support pediatric research posing minimal risk and research posing greater risk if it has high social value

High-Fiber Diet May Benefit Melanoma Patients on Immunotherapy

Higher intake of dietary fiber linked to longer progression-free survival in melanoma patients on immune checkpoint blockade

COVID-19-Related Alcohol Consumption Will Increase Liver Disease

One-year increase in alcohol consumption to result in 8,000 additional liver disease-related deaths