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As ruling was announced, the president of the AMA reaffirmed the group's support for policies that reduce U.S. greenhouse gas emissions

E-Noses Promising for Diagnosing Cancer from Exhaled Breath

Electronic noses detect volatile organic compounds in exhaled breath to diagnose cancer

NHS Privatization Tied to Increase in Treatable Mortality

Annual increase of 1 percent of outsourcing to the private for-profit sector linked to annual increase of 0.38 percent in treatable mortality

Prevalence of CRC Screening Remains Low in Those Aged 50 to 54

Increase in screening differed by age, with 19.4 percent increase for those aged 50 to 54 and 31.6 percent increase for those aged 70 to 75

Hormone Therapy-Related Hot Flashes Tied to Worse Breast Cancer Outcomes

Findings for chemotherapy-free patients with breast cancer

JCAHO Standards Not Always Supported by High-Quality Evidence

Of 20 actionable standards from The Joint Commission, six completely supported by references, six partly supported

10-Year Weight Gain Substantial for U.S. Adults

Younger adults, women, and Non-Hispanic Blacks have highest levels of 10-year weight gain

1990 to 2019 Saw Decrease in Global Burden of Childhood Cancer

Decreases in all regions, but highest rates in 2019 seen in countries with lower sociodemographic index

Life Expectancy in the U.S. Varies by Race, Ethnicity, State

Disparity in life expectancy across states greater when race/ethnicity are considered

Enzalutamide Active in Low-, Intermediate-Risk Prostate Cancer

Significant reduction seen in risk of prostate cancer progression for enzalutamide plus AS versus active surveillance alone

Exercise Improves Global Longitudinal Strain in Breast Cancer Survivors

Significantly lower risks of abnormal GLS for moderately active and active survivors versus those who are inactive

Donor Sex, Parity Do Not Up Mortality for Red Blood Cell Recipients

After adjustment for donor hemoglobin levels, no increased risk seen for requiring additional transfusion after transfusion from female donor

Factors ID'd in Time to Breast Biopsy by Race, Ethnicity

Multilevel factors examined for differences in time from abnormal screening mammogram to biopsy by race, ethnicity

Anemia During Pregnancy Increased Among WIC Participants

Prevalence of anemia was higher among non-Hispanic Black or African American women overall and by trimester

In AIDS-Related Lymphoma, Outcomes Worse With Hypoalbuminemia

AIDS-related lymphoma patients with hypoalbuminemia show worse overall survival, two-year progression-free survival

More Than 18 Million Cancer Survivors Living in U.S. as of Jan. 1, 2022

Considerable racial disparities seen in treatment, with surgery receipt lower for Black versus White patients with NSCLC

2015 to 2020 Saw Increase in HPV Vaccination Rates Among Teens

Larger increases in coverage seen among boys than girls, with narrowing of coverage gap

Women Remain Underrepresented in Clinical Trials

Gap seen in cardiovascular, psychiatry, and cancer trial participation versus national prevalence disease data

Maternal Deaths Up With Pregnancies Complicated by Cancer

U.S. prevalence of pregnancy complicated by cancer increased between 2016 and 2019

More African-Americans Screened for Lung Cancer With USPSTF 2021 Criteria

Expanding lung cancer screening criteria is step toward greater equity for high-risk populations

American Society of Clinical Oncology, June 3-7

The Annual Meeting of the American Society of Clinical Oncology

USPSTF Recommends Against Beta Carotene, Vitamin E Supplements

No benefit seen for cardiovascular disease, cancer prevention; evidence insufficient for assessing pros and cons of multivitamins

Medicare Could Have Saved $3.6 Billion on Generic Drugs in 2020

Authors say Medicare could have saved up to $3.6 billion by purchasing generics at Mark Cuban Cost Plus Drug Company prices

Federal Court Orders EPA to Reexamine Whether Roundup Causes Cancer

In its ruling, court challenged Trump-era finding that glyphosate was not a serious health risk and 'not likely' to cause cancer

Income, Education Linked to Advanced Stage of Diagnosis of NSCLC

Findings persist among race/ethnic groups, regardless of government or private insurance, and across facility types

Dual Effect Identified for Arsenic in Carcinogenesis

Arsenic level in drinking water negatively associated with incidences of lymphoma, leukemia in men and women

Medicaid Expansion Buffered Health Coverage Loss During Pandemic

Workers who lived in Medicaid expansion states were 5.4 percent more likely to enroll in Medicaid after job loss during pandemic

Disparities in Life Expectancy by Race, Ethnicity, County Persist

In the U.S., increases in life expectancy were seen for Black, API, Latino, White populations, but no change seen for AIAN

IV Vitamin C Increases Risk for Death, Organ Failure in Sepsis

Risk increased with intravenous vitamin C versus placebo for adults with sepsis in the ICU receiving vasopressor therapy

No Fewer Deaths Seen With Restricted IV Fluid for Septic Shock

Rates of death at 90 days, SAEs did not differ for patients with septic shock receiving restricted versus standard IV fluid therapy in the ICU

Treating Anal HSIL Cuts Anal Cancer Risk in Persons With HIV

Rate of progression to anal cancer lower for those receiving treatment of anal high-grade squamous intraepithelial lesions

Higher Dairy Intake May Up Risk for Prostate Cancer

However, association does not hold for nondairy calcium intake

Veterans Report Low Rates of Adverse Events With mRNA Vaccines

Rates slightly higher at 42 days for those receiving Pfizer versus Moderna

Study Compares DBT With Digital Mammography Screening

Digital breast tomosynthesis linked to lower risk of advanced breast cancer for women with extremely dense breasts, high risk for breast cancer

Disruption to Oncology Clinical Trials Seen Early in Pandemic

Numbers of new patient accruals and newly activated trials decreased early on, followed by progressive recovery

Sugar-Sweetened Drinks May Raise Risk for Liver Cancer

Hazard ratio of 1.78 for consumption of one or more SSB/day compared with never consumption for older women

Healthy Plant-Based Diet May Cut Breast Cancer Risk

Adherence to unhealthful plant-based diet linked to increased risk of ER+ breast cancer and lobular carcinoma

Relative Risk for CVT Up After AZD1222 COVID-19 Vaccine

Relative rates of hospital contacts for coagulation disorder, cerebrovascular disease increased after AZD1222 vaccination

New Cancer Drugs Approved Faster in U.S. Than Europe

FDA received licensing applications sooner and had shorter review times, compared to the European Medicines Agency

2016 to 2020 Saw Increase in Medical Cannabis Licensure

Percent of patients with conditions that had substantial or conclusive evidence of therapeutic value decreased from 2016 to 2020

Hospital Interns Spend Only 13.4 Percent of Time in Patient Rooms

Real-time locating systems may be used to improve the training experience, authors say

AACR: Cancer Disparities Represent Ongoing Public Health Challenge

Discriminatory policies, systemic inequities, structural barriers resulting from history of racism cause and perpetuate cancer health disparities

Half of Hospitals Have Implemented No Price Transparency

Only 5.7 percent of hospitals meet both requirements -- a machine-readable file for required price types and an accessible display for at least 300 shoppable items

Screening Mammography Levels Not Fully Restored After Pandemic Drop

While mammography, biopsies, and cancer diagnoses are up from 2020 lows, none have reached pre-COVID-19 volumes

Risk of New-Onset Type 2 Diabetes Up After Cancer Diagnosis

Adults with new onset type 2 diabetes in two years after diagnosis had increased risk of all-cause mortality

Higher Fish Intake May Increase Melanoma Risk

Higher total fish intake, tuna intake, nonfried fish intake positively linked to risks of malignant melanoma, melanoma in situ

Research Needed to Understand Impact of Low-Dose Radiation

Estimated $100 million needed annually for the next 10 to 15 years to conduct epidemiological, biological research

Perception of E-Cigarettes as More Harmful Increased 2019 to 2020

Exclusive cigarette smoking increased among those who perceived e-cigarettes as relatively more harmful

ASCO: Ramucirumab Plus Pembrolizumab Promising in NSCLC

In phase 2 trial, overall survival longer with combo treatment compared with investigator's choice for standard of care in advanced NSCLC

Bariatric Surgery Cuts Obesity-Related Cancer Incidence

Findings seen in large study of obese adults with and without surgery, followed for 10 years

New Drug Launch Prices Increasing Exponentially Each Year

Findings among newly marketed brand-name prescription drugs launched in 2008 to 2021

ADT + Pelvic Lymph Node Radiation Improves Prostate Cancer Outcomes

Five-year freedom from progression rate higher for those receiving short-term ADT and PLNRT in addition to salvage PBRT

Additional Biopsies After CRC Biopsy Not Tied to Metachronous CRC

Biopsy of nontumor sites after initial colorectal cancer biopsy not linked to risk for metachronous cancer

Actions Against Physician Licenses Due to Substance Use Down

However, despite declines from 2004 to 2020, substance use-related actions remain much higher than actions for physical, psychological impairment

ASCO: Risk for Suicide Elevated in Cancer Patients in the U.S.

Standardized mortality ratio for suicide decreased from 2000 to 2016, but risk remains elevated, especially within first two years of diagnosis

Survivors of Childhood Cancer More Likely to Be Undertreated for CVD

Increased health-related self-efficacy associated with significantly reduced likelihood of undertreatment

ASCO: Ancestry-Specific Genetic Risk Examined for TNBC

Magnitudes of gene-specific risks for triple-negative breast cancer similar across racial/ethnic groups

ASCO: Black Patients With Metastatic Breast Cancer Willing to Consider Clinical Trials

40 percent of respondents reported that care team had not discussed trials; concerns about side effects, effectiveness limit participation

ASCO: Disparities Seen in Telehealth Use for Cancer Care During Pandemic

Disparities according to race, geographic location, socioeconomic status seen for telehealth use among patients initiating cancer treatment

ASCO: Desmoplastic Melanoma Responds to Neoadjuvant Pembrolizumab

Fifty-six percent of patients had pathologic complete response after neoadjuvant treatment with pembrolizumab

ASCO: ACA Medicaid Expansion Has Increased Access to Cancer Trials

Proportion of SWOG trial participants who had Medicaid insurance increased by 20 percent per year after ACA Medicaid expansion

ASCO: Parental Cancer Tied to Risk for Unmet Social Needs in Children

Unmet social needs include family-level food insecurity, financial worry about housing costs and other monthly bills, and transportation challenges

ASCO: ctDNA Analysis Guides Treatment of Stage II Colon Cancer

ctDNA-guided approach to determining the need for adjuvant therapy noninferior to standard management for recurrence-free survival

Bridge Therapy Between Induction, ASCT May Slow Neuroblastoma

Three-year event-free survival significantly improved for patients with end-induction stable metastatic disease receiving bridge therapy

ASCO: Increase in Cancer-Related Death Seen During Pandemic

Cancer-related monthly mortality rate higher in April 2020 when health care capacity was most challenged

AE Risk Examined for Abiraterone, Enzalutamide in Prostate Cancer

Risk for metabolic or cardiovascular adverse events increased for men receiving abiraterone or enzalutamide for advanced disease

Radiation Segmentectomy Efficacious for Unresectable Liver Cancer

All patients had initial objective response and 90 percent had sustained complete response; few patients had high-grade adverse events

Metformin Does Not Improve Survival in High-Risk Breast Cancer

Incidence rate of invasive disease-free survival events and incidence rates for death did not differ with addition of metformin, placebo

Breast, Cervical Cancer Screening Decreased From 2018 to 2020

Prevalence of CRC screening remained stable with increase in stool testing offsetting decrease in colonoscopy

ASCO: Add-On Ibrutinib Slows Mantle-Cell Lymphoma in Older Adults

Addition of ibrutinib to chemoimmunotherapy prolongs progression-free survival in older patients with untreated mantle-cell lymphoma

Eating Red Meat May Up Colorectal Cancer Risk in Black Women

Intake of unprocessed red meat associated with 33 percent increased risk for colorectal cancer per 100 g/day in Black women