Lippincott ^® NursingCenter ^®

Risk for aging-related health conditions increased with consumption of more total sugar, added sugar, and sugar-sweetened beverages

FDA Approves First Gene Therapy for Adults With Hemophilia B

Benefits include decreased need for routine factor IX replacement prophylaxis and reduction in annualized bleeding rate

QOL Up With Pembrolizumab Versus Ipilimumab, HDI in Resected Melanoma

Quality of life favored the pembrolizumab arm versus standard-of-care arm receiving ipilimumab, high-dose interferon α 2b

Cervical Cancer Incidence Up Among Women Ages 30 to 34 Years

Findings similar across most races and cancer stages from 2012 to 2019

Robotic Resection Cuts Perioperative Morbidity With Liver Cancer

Overall survival and cumulative incidence of death related to tumor recurrence similar to open resection

Five-Year Relative Survival 59.6 Percent in Lower-Risk Myelodysplastic Syndromes

Five-year overall survival 47.3 percent in patients with lower-risk myelodysplastic syndromes

Adherence to Quality Indicators Low in Chronic Myeloid Leukemia

Compliance with diagnostic and therapeutic indicators was 83 and 78 percent, while compliance with monitoring indicators was lower

Decrease Noted in Lung Cancer Cases Over Past Five Years

However, screening of high-risk individuals for lung cancer is still low at 5.8 percent nationally

Adults Lack Knowledge About Signs of Pancreatic Cancer

Pancreatic Cancer Action Network survey revealed knowledge gaps exist across ages, genders

Significant Treatment Attrition Rate Seen in Multiple Myeloma

In patients receiving autologous stem cell transplant, 57.6 percent advanced to second-line treatment, 32.6 percent to third-line

Oncogenic Variants Identified in ~10 Percent With Appendix Cancer

Mutations identified in MUTYH, in the MLH1 gene, and in other cancer predisposition genes

Most Pivotal Trials of New Drugs Recruit From Low-, Middle-Income Countries

Percentage of participants recruited from low-, middle-income countries was 8, 36, and 17 percent for cancer, cardiovascular, neurology trials

Treatment-Related Adverse Events of Antibody Drug Conjugates Identified

Overall incidence of treatment-related adverse events was 91.2 percent and included lymphopenia, nausea, neutropenia

Treatment Without ADT Delays Initiation of Systemic Therapy in Prostate Cancer

Metastasis-directed therapy can delay initiation of systemic therapy in patients with solitary oligorecurrent metastatic lesion

FDA: Patients Should Be Cautious When Using Online Pharmacies to Buy Meds

Red flags include pharmacies that do not require a doctor's prescription or have a licensed pharmacist to answer questions

Cancer Screening and Detection Remain Below Prepandemic Levels

Lower screening rates for cervical, breast, and colorectal cancers suggest 'pattern of forgone care,' according to researchers

Cancer Mortality Up With Residential Racial, Economic Segregation

Segregation was associated with increased mortality for 12 of 13 cancer sites examined

Even Moderate Exercise Linked to Reduced Mortality After Breast Cancer

Breast cancer survivors who were active or moderately active had significantly reduced risk for death

Artificial Intelligence-Aided Colonoscopy Does Not Increase Cancer Detection

AIAC group had lower adenoma and polyp detection rates; lower median number of adenomas, polyps detected per colonoscopy

Shorter Regimen of Radiotherapy Safe for Soft Tissue Sarcoma

Findings with preoperative radiotherapy administered to dose of 42.75 Gy in 15 fractions for three weeks

FDA Oversight of Clinical Trials Described as 'Grossly Inadequate'

Article describes inadequate oversight relating to development of COVID-19 vaccines and predating the pandemic

Multidimensional Factors Shaped Physician Stress During Pandemic

Physicians' perceptions of occupational stress at individual level were shaped by stressors within and across four levels

FDA Approves Drug Combo for Metastatic Non-Small Cell Lung Cancer

Approval is for tremelimumab in combination with durvalumab and platinum-based chemotherapy

Parkinsonism, Parkinson Disease Risk Up With Bilateral Oophorectomy Before 43

Risk increased in premenopausal women undergoing oophorectomy for benign indication before age 43 years

Acupuncture Reduces Aromatase Inhibitor-Related Joint Pain

Findings observed in women with early-stage breast cancer who were taking an aromatase inhibitor and had a score of 3 or higher on BPI-WP item

California Voters Ban Flavored Tobacco, and a Cigarette Maker Is Suing

R.J. Reynolds has sued California over its freshly approved ban on flavored tobacco products

California Files Suit Over 'Forever Chemicals' in Water

California has sued several companies over their role in dumping 'forever chemicals' into the state's water systems, in an effort to get them to pay cleanup costs

Health Care Access May Affect Receipt of Therapy in Ovarian Cancer

Among ovarian cancer patients, non-Hispanic Blacks remained less likely than non-Hispanic Whites to initiate systemic therapy even after adjustment for health care access scores

Nab-Paclitaxel, Pembrolizumab Combo Active in Advanced Urothelial Cancer

Overall response rate 50 percent among 36 patients with platinum-refractory or cisplatin-ineligible advanced urothelial cancer

Options Explored for MM That Relapses After BCMA CAR T Therapy

Salvage treatments and outcomes examined for patients with multiple myeloma that relapses after B-cell maturation antigen-directed CAR T therapy

Overall Cancer Mortality 18 Percent Higher in AI/AN Versus Whites

Breast and prostate mortality rates 8 and 31 percent higher, despite lower incidence rates

American Society for Radiation Oncology, Oct. 23-26

The 64th Annual Meeting of the American Society for Radiation Oncology

Subset of Stage I Melanoma Patients ID'd With Very Low Mortality

Younger age at diagnosis, Clark level II linked to low risk for death among patients with stage I lesions, negative clinical nodes

Electroacupuncture Cuts Risk for Prolonged Postoperative Ileus

Findings seen among patients recovering from laparoscopic resection of colorectal cancer

Frailty-Related Fracture Risk Higher for Seniors With Cancer History

Cancer survivors who received chemotherapy more likely to have fracture; link stronger within five years of diagnosis

Brentuximab Vedotin + Chemo Ups Event-Free Survival in Peds Hodgkin Lymphoma

Event-free survival rate higher in pediatric patients, but no difference seen in the percentage of patients receiving involved-site radiation therapy

Older Adults With Poor-Prognosis Cancers Commonly Have Preexisting Conditions

These preexisting conditions impact functional impairment, mobility, falls

Top Medical Groups, Hospitals Urge Better Access to Lung Cancer Screening

More than 50 cancer groups have issued an urgent call for more lung cancer screening among high-risk people

Surveillance Feasible for Women Deferring Prophylactic Salpingo-Oophorectomy

Ovarian cancer surveillance has modeled sensitivity and specificity of 87.5 and 99.9 percent and is cost-saving

Sequencing of ADT, RT Examined in Localized Prostate Cancer

Pooled analysis of 12 randomized trials suggests use of concurrent/adjuvant androgen deprivation therapy in combination with prostate-only radiotherapy may improve outcomes

Cancer Death Rates Continuing to Decline for Adults, Children

Incidence remained stable among men and increased among women during 2014 to 2018

Patients Favor Single-Port Robotic System for Uro-Oncology Surgery

Patients in the single-port versus multiport system group reported better cosmetic appearance, higher satisfaction with cosmetic appearance of surgical scar

ASTRO: Medical Physicist-Patient Consult May Ease Stress of RT

Benefits may include decreased anxiety, increased technical and overall satisfaction

ASTRO: Sexual Function After Brachytherapy Less Often Assessed in Women

Sexual function less likely to be assessed in women versus men undergoing brachytherapy for genitourinary cancers