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'Test-to-Treat' program is part of federal and city efforts to catch and treat infections early and be ready for new waves of the pandemic

Provider Availability Linked to COVID-19 Vaccine Uptake in Children

Vaccination coverage for children aged 5 to 11 higher in counties with at least one active COVID-19 vaccine provider versus no provider

Vaccination Protects Overweight, Obese Against Severe COVID-19

Protection against severe COVID-19 similar for those with overweight, obesity versus healthy weight; lower protection seen for underweight

Twelve-Week Treatment Regimen Reduces Facial Redness

Skin seemed less inflamed, improvement seen in overall skin appearance, and skin looked and felt healthier

FDA Tells Vaccine Makers to Update Boosters to Target Omicron Subvariants

Pfizer and Moderna are expected to start producing reformulated doses this summer

U.S. Orders 105 Million More Pfizer Shots for Fall Booster Campaign

Both Pfizer and Moderna have reported positive results with updated vaccines that target the omicron variant

Doctors May Under-Prescribe Pain Meds During Night Shifts

Physicians less likely to prescribe an analgesic during night shifts versus daytime shifts

NHS Privatization Tied to Increase in Treatable Mortality

Annual increase of 1 percent of outsourcing to the private for-profit sector linked to annual increase of 0.38 percent in treatable mortality

Opioid Tapering Tied to Overdose, Withdrawal, Mental Health Risks for Up to Two Years

Authors hope findings will 'inform a more cautious approach to decisions around opioid dose tapering'

Hormone Therapy-Related Hot Flashes Tied to Worse Breast Cancer Outcomes

Findings for chemotherapy-free patients with breast cancer

JCAHO Standards Not Always Supported by High-Quality Evidence

Of 20 actionable standards from The Joint Commission, six completely supported by references, six partly supported

PrEP Stigma High Among U.S. Male Couples

Additionally, men underestimate effectiveness of PrEP

Life Expectancy in the U.S. Varies by Race, Ethnicity, State

Disparity in life expectancy across states greater when race/ethnicity are considered

Pfizer Has Two Updated Booster Shots to Help Fight Omicron

Company said Saturday that it was confident its new booster candidates are better than their predecessor

FDA Panel to Weigh Improved Booster Shots From Moderna, Pfizer

Both Pfizer and Moderna have been testing updated booster shots that target the omicron variant

Enzalutamide Active in Low-, Intermediate-Risk Prostate Cancer

Significant reduction seen in risk of prostate cancer progression for enzalutamide plus AS versus active surveillance alone

Fourth Dose of BNT162b2 Prevents Severe COVID-19 in Nursing Home Residents

Substantial protection against hospitalizations, deaths seen among long-term care facility residents during omicron surge

CDC Backs Moderna Vaccine for Those Aged 6 to 17

ACIP endorsed the shots after hearing the latest evidence on the vaccine's effectiveness

New York City Opens First Monkeypox Vaccine Clinic in U.S.

Announcement follows similar ones issued from the United Kingdom and Canada

SCOTUS Overturns Roe v. Wade, Leaving Many Women Without Access to Abortion

Decision sets the stage for a swift rollback of abortion rights in more than half of the United States

One in 10 Pain Meds Make It Through Development Process

More drugs with high abuse potential made it through the development process than new drugs with low abuse potential

2015 to 2020 Saw Increase in HPV Vaccination Rates Among Teens

Larger increases in coverage seen among boys than girls, with narrowing of coverage gap

Women Remain Underrepresented in Clinical Trials

Gap seen in cardiovascular, psychiatry, and cancer trial participation versus national prevalence disease data

Challenge Study Shows Efficacy of RSV Vaccine in Healthy Adults

Bivalent prefusion F RSV vaccine effective against symptomatic RSV infection and viral shedding in phase 2a study

Cost of Ranibizumab Port Delivery System for Treating nAMD Examined

Model compares costs for ranibizumab port delivery system versus conventional intravitreal antivascular endothelial growth factor injections

Tampons Are in Short Supply Across United States

Shortages are being caused by supply problems getting cotton and plastic

Primary Care Outreach Boosts COVID-19 Vaccination Rates

Electronic and mail messages from primary care providers increased COVID-19 vaccination rates among Black and Latino older adults

American Society of Clinical Oncology, June 3-7

The Annual Meeting of the American Society of Clinical Oncology

USPSTF Recommends Against Beta Carotene, Vitamin E Supplements

No benefit seen for cardiovascular disease, cancer prevention; evidence insufficient for assessing pros and cons of multivitamins

Medicare Could Have Saved $3.6 Billion on Generic Drugs in 2020

Authors say Medicare could have saved up to $3.6 billion by purchasing generics at Mark Cuban Cost Plus Drug Company prices

With CDC Approval, COVID-19 Shots for Under 5s Ready for Delivery

Health officials have said the federal government will be ready to ship doses out this week

FDA Approves Skyrizi for Moderately to Severely Active Crohn Disease

Skyrizi is first specific interleukin-23 approved to treat Crohn disease

Azithromycin Improves Outcomes in Poorly Controlled Child Asthma

Better control, fewer exacerbations seen with addition of oral azithromycin to standard therapy in children with poorly controlled asthma

Medicaid Expansion Buffered Health Coverage Loss During Pandemic

Workers who lived in Medicaid expansion states were 5.4 percent more likely to enroll in Medicaid after job loss during pandemic

Disparities in Life Expectancy by Race, Ethnicity, County Persist

In the U.S., increases in life expectancy were seen for Black, API, Latino, White populations, but no change seen for AIAN

ENDO: Fracture Risk Up With Insulin Compared With Metformin in T2DM

Risk for major osteoporotic fractures up for insulin versus metformin for those with HbA1c <7 percent, BMI <25 kg/m²

Abbott Infant Formula Plant Closed Again After Flooding

After the plant is resanitized, Abbott said it will resume making EleCare, followed by specialty and metabolic formulas

Veterans Report Low Rates of Adverse Events With mRNA Vaccines

Rates slightly higher at 42 days for those receiving Pfizer versus Moderna

Genetic Variants in HMGCR Linked to Increased Cataract Risk

Heterozygous carriers of HMGCR predicted loss-of-function variants had higher risks for developing cataract, cataract surgery

Atogepant Prevents Migraine in Adults

Compared with placebo, increase in responder rates seen at all atogepant dose levels

ENDO: Guidelines Updated for Hospitalized Adults With Hyperglycemia

Guidelines address glycemic management in noncritically ill hospitalized adults with diabetes or newly recognized hyperglycemia

Relative Risk for CVT Up After AZD1222 COVID-19 Vaccine

Relative rates of hospital contacts for coagulation disorder, cerebrovascular disease increased after AZD1222 vaccination

New Cancer Drugs Approved Faster in U.S. Than Europe

FDA received licensing applications sooner and had shorter review times, compared to the European Medicines Agency

2016 to 2020 Saw Increase in Medical Cannabis Licensure

Percent of patients with conditions that had substantial or conclusive evidence of therapeutic value decreased from 2016 to 2020

Half of Hospitals Have Implemented No Price Transparency

Only 5.7 percent of hospitals meet both requirements -- a machine-readable file for required price types and an accessible display for at least 300 shoppable items

Lutein/Zeaxanthin in AREDS2 May Slow Progression to Late AMD

No increased risk for lung cancer, reduced risk for progression to late AMD seen with lutein/zeaxanthin as replacement for beta-carotene

ASCO: Ramucirumab Plus Pembrolizumab Promising in NSCLC

In phase 2 trial, overall survival longer with combo treatment compared with investigator's choice for standard of care in advanced NSCLC

New Drug Launch Prices Increasing Exponentially Each Year

Findings among newly marketed brand-name prescription drugs launched in 2008 to 2021

Risk for SARS-CoV-2 Breakthrough Infections Up in Persons With HIV

Risk for breakthrough infections increased in association with younger age, history of COVID-19, not receiving additional vaccine dose

ASCO: Black Patients With Metastatic Breast Cancer Willing to Consider Clinical Trials

40 percent of respondents reported that care team had not discussed trials; concerns about side effects, effectiveness limit participation

ASCO: Desmoplastic Melanoma Responds to Neoadjuvant Pembrolizumab

Fifty-six percent of patients had pathologic complete response after neoadjuvant treatment with pembrolizumab

Vaccination Status Affects Patient Willingness to Have Surgery During Pandemic

In hypothetical scenarios for a viral pandemic, willingness for surgery was higher with both patients and hospital staff vaccinated

2016 to 2019 Saw Drop in Patients Receiving Opioids, Benzodiazepines

Relative change from 2016 to 2019 varied from −52.0 percent in Mississippi to −6.9 percent in New Hampshire

Abbott Baby Formula Plant Tied to Shortage Reopens

Production of EleCare specialty formulas for infants with severe food allergies and digestive problems will be given top priority

ASCO: ctDNA Analysis Guides Treatment of Stage II Colon Cancer

ctDNA-guided approach to determining the need for adjuvant therapy noninferior to standard management for recurrence-free survival

ADA: Tirzepatide Improves Kidney Outcomes in T2DM With Increased CV Risk

Fewer renal complications seen with tirzepatide versus insulin glargine in adults with T2D and increased cardiovascular risk

AE Risk Examined for Abiraterone, Enzalutamide in Prostate Cancer

Risk for metabolic or cardiovascular adverse events increased for men receiving abiraterone or enzalutamide for advanced disease

Metformin Does Not Improve Survival in High-Risk Breast Cancer

Incidence rate of invasive disease-free survival events and incidence rates for death did not differ with addition of metformin, placebo